Pharmacological Evaluation of New Baclofen Derivatives

The synthesis and in‐vivo central pharmacological properties, in particular antinociceptive activity, of some new baclofen derivatives is described. The delayed antinociceptive activity of the N‐trifluoroacetyl analogue of baclofen is also characterized.

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Veröffentlicht in:Pharmacy and Pharmacology Communications 1999-03, Vol.5 (3), p.243-247
Hauptverfasser: GUILLON, JEAN, LEVASSEUR, VÉRONIQUE, SONNET, PASCAL, STIEBING, SILVIA, BOULOUARD, MICHEL, DALLEMAGNE, PATRICK, QUERMONNE, MARIE-ANNE, RAULT, SYLVAIN
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Sprache:eng
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Zusammenfassung:The synthesis and in‐vivo central pharmacological properties, in particular antinociceptive activity, of some new baclofen derivatives is described. The delayed antinociceptive activity of the N‐trifluoroacetyl analogue of baclofen is also characterized.
ISSN:1460-8081
2042-7158
DOI:10.1211/146080899128734686