How Molecular Mobility, Physical State, and Drug Distribution Influence the Naproxen Release Profile from Different Mesoporous Silica Matrices

Aiming to evaluate how the release profile of naproxen (nap) is influenced by its physical state, molecular mobility, and distribution in the host, this pharmaceutical drug was loaded in three different mesoporous silicas differing in their architecture and surface composition. Unmodified and partia...

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Veröffentlicht in:	Molecular pharmaceutics 2021-03, Vol.18 (3), p.898-914
Hauptverfasser:	d’Orey, Piedade, Cordeiro, Teresa, Lourenço, Mirtha A. O, Matos, Inês, Danède, Florence, Sotomayor, João C, Fonseca, Isabel M, Ferreira, Paula, Correia, Natália T, Dionísio, Madalena
Format:	Artikel
Sprache:	eng
Schlagworte:	Condensed Matter Disordered Systems and Neural Networks Materials Science Physics Soft Condensed Matter
Online-Zugang:	Volltext
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