Structural aspects of Vitamin D endocrinology

1α,25-Dihydroxvitamin D3 (1,25(OH)2D3) is the hormonally active form of vitamin D3. Its synthesis and its metabolites, their transport and elimination as well as action on transcriptional regulation involves the harmonic cooperation of diverse proteins with vitamin D binding capacities such as vitam...

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Veröffentlicht in:	Molecular and cellular endocrinology 2017-09, Vol.453, p.22-35
Hauptverfasser:	Rochel, Natacha, Molnár, Ferdinand
Format:	Artikel
Sprache:	eng
Schlagworte:	Allosteric Regulation Allostery Biochemistry, Molecular Biology Cholecalciferol - chemistry Cholecalciferol - genetics Cholecalciferol - metabolism Cholestanetriol 26-Monooxygenase - chemistry Cholestanetriol 26-Monooxygenase - metabolism CYPs Cytochrome P450 Family 2 - chemistry Cytochrome P450 Family 2 - metabolism DBP Gene Expression Regulation Humans HVDRR Life Sciences Models, Molecular Mutation Receptors, Calcitriol - chemistry Receptors, Calcitriol - genetics Receptors, Calcitriol - metabolism Rickets, Hypophosphatemic - genetics Structure VDR Vitamin D-Binding Protein - chemistry Vitamin D-Binding Protein - metabolism Vitamin D3 Vitamin D3 24-Hydroxylase - chemistry Vitamin D3 24-Hydroxylase - metabolism
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