NMR and crystallographic structural studies of the Elongation factor P from Staphylococcus aureus

Elongation factor P (EF-P) is a translation protein factor that plays an important role in specialized translation of consecutive proline amino acid motifs. EF-P is an essential protein for cell fitness in native environmental conditions. It regulates synthesis of proteins involved in bacterial moti...

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Veröffentlicht in:	European biophysics journal 2020-05, Vol.49 (3-4), p.223-230
Hauptverfasser:	Golubev, Alexander, Fatkhullin, Bulat, Gabdulkhakov, Azat, Bikmullin, Aydar, Nurullina, Liliya, Garaeva, Natalia, Islamov, Daut, Klochkova, Evelina, Klochkov, Vladimir, Aganov, Albert, Khusainov, Iskander, Validov, Shamil, Yusupova, Gulnara, Yusupov, Marat, Usachev, Konstantin
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Antibiotic resistance Antibiotics Bacteria Bacterial Proteins - chemistry Bacterial Proteins - metabolism Biochemistry Biochemistry, Molecular Biology Biological and Medical Physics Biomedical and Life Sciences Biophysics Cell Biology Crystal structure Crystallography Crystallography, X-Ray Drug development Elongated structure Elongation Environmental conditions Life Sciences Membrane Biology Models, Molecular Nanotechnology Neurobiology NMR Nuclear magnetic resonance Nuclear Magnetic Resonance, Biomolecular Original Article Peptide Elongation Factors - chemistry Peptide Elongation Factors - metabolism Proline Protein Domains Proteins Staphylococcus aureus Therapeutic targets Translation Virulence
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