How can we define the presymptomatic C9orf72 disease in 2022? An overview on the current definitions of preclinical and prodromal phases

Repeat expansions in C9orf72 gene are the main genetic cause of frontotemporal dementia, amyotrophic lateral sclerosis and related phenotypes. With the advent of disease-modifying treatments, the presymptomatic disease phase is getting increasing interest as an ideal time window in which innovant th...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Revue neurologique 2022-05, Vol.178 (5), p.426-436
Hauptverfasser:	Saracino, D., Le Ber, I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amyotrophic lateral sclerosis Biomarker C9orf72 Cognitive science Frontotemporal dementia Frontotemporal lobar degeneration Human health and pathology Life Sciences Neuroscience Presymptomatic disease Psychiatrics and mental health
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!