Synthesis of PLA-poly(ether urethane)-PLA copolymers and design of biodegradable anti-adhesive membranes for orthopaedic applications

Peritendinous adhesions cause chronic pain and disability. Leading causes are trauma to tendons and surrounding tissues and immobilization after surgery. Adhesions occur between 24 hours to 6 weeks after surgery. Anti-adhesion barriers are currently the best option available to prevent peritendinous...

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Veröffentlicht in:	Journal of materials chemistry. B, Materials for biology and medicine Materials for biology and medicine, 2021-01, Vol.9 (3), p.832-845
Hauptverfasser:	Zebiri, Hadda, Van Den Berghe, Hélène, Sayegh, Syreina, Chammas, Pierre-Emmanuel, Pompée, Christian, Chammas, Michel, Garric, Xavier
Format:	Artikel
Sprache:	eng
Schlagworte:	Adhesion Animals Biocompatibility Biocompatible Materials Biocompatible Materials - chemical synthesis Biocompatible Materials - chemistry Biodegradability Biodegradation Block copolymers Cell Line Chronic pain Contact angle Copolymers Cytotoxicity Degradation Ethyl carbamate Hydrophobic and Hydrophilic Interactions Immobilization In vivo methods and tests Life Sciences Mechanical properties Medical equipment Membranes Mice Molecular Structure Orthopedics Pain Particle Size Polyesters Polyesters - chemistry Polyethylene glycol Polylactic acid Polyurethanes Polyurethanes - chemistry Surface Properties Surgery Temperature Tendons Tissue Adhesions Tissue Adhesions - prevention & control Toxicity Trauma Water uptake
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