EPR spectroscopic evidence of iron-catalysed free radical formation in chronic mountain sickness: Dietary causes and vascular consequences

Chronic mountain sickness (CMS) is a high-altitude (HA) maladaptation syndrome characterised by elevated systemic oxidative-nitrosative stress (OXNOS) due to a free radical-mediated reduction in vascular nitric oxide (NO) bioavailability. To better define underlying mechanisms and vascular consequen...

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Veröffentlicht in:	Free radical biology & medicine 2022-05, Vol.184, p.99-113
Hauptverfasser:	Bailey, Damian M., Culcasi, Marcel, Filipponi, Teresa, Brugniaux, Julien V., Stacey, Benjamin S., Marley, Christopher J., Soria, Rodrigo, Rimoldi, Stefano F., Cerny, David, Rexhaj, Emrush, Pratali, Lorenza, Salmòn, Carlos Salinas, Jáuregui, Carla Murillo, Villena, Mercedes, Villafuerte, Francisco, Rockenbauer, Antal, Pietri, Sylvia, Scherrer, Urs, Sartori, Claudio
Format:	Artikel
Sprache:	eng
Schlagworte:	Altitude Altitude Sickness - metabolism Carotid Intima-Media Thickness Chronic Disease Chronic mountain sickness Electron Spin Resonance Spectroscopy Endocrinology and metabolism Food and Nutrition Free Radicals Human health and pathology Humans Iron Life Sciences Male Oxidative catalysis Oxidative-nitrosative stress Pulse Wave Analysis Systemic vascular function
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