Organotropism and biomarker response in oyster Crassostrea gigas exposed to platinum in seawater
Platinum (Pt) is a technology critical element (TCE) for which biogeochemical cycles are still poorly understood. This lack of knowledge includes Pt effects on marine organisms, which proved to be able to bioconcentrate this trace element. Oysters Crassostrea gigas were exposed to stable Pt isotope...
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| Veröffentlicht in: | Environmental science and pollution research international 2020-02, Vol.27 (4), p.3584-3599 |
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| creator | Abdou, Melina Zaldibar, Beñat Medrano, Rebeca Schäfer, Jörg Izagirre, Urtzi Dutruch, Lionel Coynel, Alexandra Blanc, Gérard Soto, Manu |
| description | Platinum (Pt) is a technology critical element (TCE) for which biogeochemical cycles are still poorly understood. This lack of knowledge includes Pt effects on marine organisms, which proved to be able to bioconcentrate this trace element. Oysters
Crassostrea gigas
were exposed to stable Pt isotope spiked daily in seawater for 35 days. Seawater was renewed daily and spiked (with Pt(IV)) to three nominal Pt concentrations (50, 100, and 10,000 ng L
−1
) for two replicate series. Organotropism study revealed that gills, and to a lesser extent mantle, are the key organs regarding Pt accumulation, although a time- and concentration-dependent linear increase in Pt levels occurred in all the organs investigated (i.e., digestive gland, gonads, gills, mantle, and muscle). In oysters exposed to Pt concentrations of 10,000 ng L
−1
, significant biomarker impairments occurred, especially at cellular levels. They reflect altered lipofuscin and neutral lipid contents, as well as intralysosomal metal accumulation. These observations were attributed to activation of excretion/detoxification mechanisms, including Pt elimination through feces and clearly support the importance of the digestive gland in the response to direct Pt exposure. Despite relatively constant condition index, the integrative biological response (IBR) index suggests a generally decreasing health status of oysters. |
| doi_str_mv | 10.1007/s11356-018-3443-7 |
| format | Article |
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Crassostrea gigas
were exposed to stable Pt isotope spiked daily in seawater for 35 days. Seawater was renewed daily and spiked (with Pt(IV)) to three nominal Pt concentrations (50, 100, and 10,000 ng L
−1
) for two replicate series. Organotropism study revealed that gills, and to a lesser extent mantle, are the key organs regarding Pt accumulation, although a time- and concentration-dependent linear increase in Pt levels occurred in all the organs investigated (i.e., digestive gland, gonads, gills, mantle, and muscle). In oysters exposed to Pt concentrations of 10,000 ng L
−1
, significant biomarker impairments occurred, especially at cellular levels. They reflect altered lipofuscin and neutral lipid contents, as well as intralysosomal metal accumulation. These observations were attributed to activation of excretion/detoxification mechanisms, including Pt elimination through feces and clearly support the importance of the digestive gland in the response to direct Pt exposure. Despite relatively constant condition index, the integrative biological response (IBR) index suggests a generally decreasing health status of oysters.</description><identifier>ISSN: 0944-1344</identifier><identifier>EISSN: 1614-7499</identifier><identifier>DOI: 10.1007/s11356-018-3443-7</identifier><identifier>PMID: 30357671</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Accumulation ; Animal biology ; Animals ; Aquatic Pollution ; Atmospheric Protection/Air Quality Control/Air Pollution ; Bioaccumulation ; Biogeochemical cycles ; Biomarkers ; Connective tissue ; Crassostrea - drug effects ; Crassostrea - physiology ; Crassostrea gigas ; Detoxification ; Digestive glands ; Earth and Environmental Science ; Ecotoxicology ; Environment ; Environmental Chemistry ; Environmental Health ; Environmental science ; Excretion ; Exposure ; Gills ; Gonads ; Invertebrate Zoology ; Kinetics ; Laboratories ; Life Sciences ; Lipids ; Mantle ; Marine organisms ; Metals ; Mollusks ; Morphology ; Multi-Stressors in Freshwater and Transitional Environments: from Legacy Pollutants to Emerging Ones ; Muscles ; Organisms ; Organotropism ; Organs ; Oysters ; Physiology ; Platinum ; Platinum - toxicity ; Pollutants ; Seawater ; Seawater - chemistry ; Shellfish ; Time dependence ; Toxicology ; Trace elements ; Tropism - drug effects ; Waste Water Technology ; Water Management ; Water Pollutants, Chemical - toxicity ; Water Pollution Control</subject><ispartof>Environmental science and pollution research international, 2020-02, Vol.27 (4), p.3584-3599</ispartof><rights>Springer-Verlag GmbH Germany, part of Springer Nature 2018</rights><rights>Environmental Science and Pollution Research is a copyright of Springer, (2018). All Rights Reserved.</rights><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c507t-ab8197da93331f65b0aa46becaba83553f59f5f536ae5e47f2f9d4263e8aaea13</citedby><cites>FETCH-LOGICAL-c507t-ab8197da93331f65b0aa46becaba83553f59f5f536ae5e47f2f9d4263e8aaea13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11356-018-3443-7$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11356-018-3443-7$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>230,314,780,784,885,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30357671$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://hal.science/hal-03637436$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Abdou, Melina</creatorcontrib><creatorcontrib>Zaldibar, Beñat</creatorcontrib><creatorcontrib>Medrano, Rebeca</creatorcontrib><creatorcontrib>Schäfer, Jörg</creatorcontrib><creatorcontrib>Izagirre, Urtzi</creatorcontrib><creatorcontrib>Dutruch, Lionel</creatorcontrib><creatorcontrib>Coynel, Alexandra</creatorcontrib><creatorcontrib>Blanc, Gérard</creatorcontrib><creatorcontrib>Soto, Manu</creatorcontrib><title>Organotropism and biomarker response in oyster Crassostrea gigas exposed to platinum in seawater</title><title>Environmental science and pollution research international</title><addtitle>Environ Sci Pollut Res</addtitle><addtitle>Environ Sci Pollut Res Int</addtitle><description>Platinum (Pt) is a technology critical element (TCE) for which biogeochemical cycles are still poorly understood. This lack of knowledge includes Pt effects on marine organisms, which proved to be able to bioconcentrate this trace element. Oysters
Crassostrea gigas
were exposed to stable Pt isotope spiked daily in seawater for 35 days. Seawater was renewed daily and spiked (with Pt(IV)) to three nominal Pt concentrations (50, 100, and 10,000 ng L
−1
) for two replicate series. Organotropism study revealed that gills, and to a lesser extent mantle, are the key organs regarding Pt accumulation, although a time- and concentration-dependent linear increase in Pt levels occurred in all the organs investigated (i.e., digestive gland, gonads, gills, mantle, and muscle). In oysters exposed to Pt concentrations of 10,000 ng L
−1
, significant biomarker impairments occurred, especially at cellular levels. They reflect altered lipofuscin and neutral lipid contents, as well as intralysosomal metal accumulation. These observations were attributed to activation of excretion/detoxification mechanisms, including Pt elimination through feces and clearly support the importance of the digestive gland in the response to direct Pt exposure. Despite relatively constant condition index, the integrative biological response (IBR) index suggests a generally decreasing health status of oysters.</description><subject>Accumulation</subject><subject>Animal biology</subject><subject>Animals</subject><subject>Aquatic Pollution</subject><subject>Atmospheric Protection/Air Quality Control/Air Pollution</subject><subject>Bioaccumulation</subject><subject>Biogeochemical cycles</subject><subject>Biomarkers</subject><subject>Connective tissue</subject><subject>Crassostrea - drug effects</subject><subject>Crassostrea - physiology</subject><subject>Crassostrea gigas</subject><subject>Detoxification</subject><subject>Digestive glands</subject><subject>Earth and Environmental Science</subject><subject>Ecotoxicology</subject><subject>Environment</subject><subject>Environmental Chemistry</subject><subject>Environmental Health</subject><subject>Environmental science</subject><subject>Excretion</subject><subject>Exposure</subject><subject>Gills</subject><subject>Gonads</subject><subject>Invertebrate Zoology</subject><subject>Kinetics</subject><subject>Laboratories</subject><subject>Life Sciences</subject><subject>Lipids</subject><subject>Mantle</subject><subject>Marine organisms</subject><subject>Metals</subject><subject>Mollusks</subject><subject>Morphology</subject><subject>Multi-Stressors in Freshwater and Transitional Environments: from Legacy Pollutants to Emerging Ones</subject><subject>Muscles</subject><subject>Organisms</subject><subject>Organotropism</subject><subject>Organs</subject><subject>Oysters</subject><subject>Physiology</subject><subject>Platinum</subject><subject>Platinum - toxicity</subject><subject>Pollutants</subject><subject>Seawater</subject><subject>Seawater - chemistry</subject><subject>Shellfish</subject><subject>Time dependence</subject><subject>Toxicology</subject><subject>Trace elements</subject><subject>Tropism - drug effects</subject><subject>Waste Water Technology</subject><subject>Water Management</subject><subject>Water Pollutants, Chemical - toxicity</subject><subject>Water Pollution 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Crassostrea gigas exposed to platinum in seawater</atitle><jtitle>Environmental science and pollution research international</jtitle><stitle>Environ Sci Pollut Res</stitle><addtitle>Environ Sci Pollut Res Int</addtitle><date>2020-02-01</date><risdate>2020</risdate><volume>27</volume><issue>4</issue><spage>3584</spage><epage>3599</epage><pages>3584-3599</pages><issn>0944-1344</issn><eissn>1614-7499</eissn><abstract>Platinum (Pt) is a technology critical element (TCE) for which biogeochemical cycles are still poorly understood. This lack of knowledge includes Pt effects on marine organisms, which proved to be able to bioconcentrate this trace element. Oysters
Crassostrea gigas
were exposed to stable Pt isotope spiked daily in seawater for 35 days. Seawater was renewed daily and spiked (with Pt(IV)) to three nominal Pt concentrations (50, 100, and 10,000 ng L
−1
) for two replicate series. Organotropism study revealed that gills, and to a lesser extent mantle, are the key organs regarding Pt accumulation, although a time- and concentration-dependent linear increase in Pt levels occurred in all the organs investigated (i.e., digestive gland, gonads, gills, mantle, and muscle). In oysters exposed to Pt concentrations of 10,000 ng L
−1
, significant biomarker impairments occurred, especially at cellular levels. They reflect altered lipofuscin and neutral lipid contents, as well as intralysosomal metal accumulation. These observations were attributed to activation of excretion/detoxification mechanisms, including Pt elimination through feces and clearly support the importance of the digestive gland in the response to direct Pt exposure. Despite relatively constant condition index, the integrative biological response (IBR) index suggests a generally decreasing health status of oysters.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>30357671</pmid><doi>10.1007/s11356-018-3443-7</doi><tpages>16</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Environmental science and pollution research international, 2020-02, Vol.27 (4), p.3584-3599 |
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| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Accumulation Animal biology Animals Aquatic Pollution Atmospheric Protection/Air Quality Control/Air Pollution Bioaccumulation Biogeochemical cycles Biomarkers Connective tissue Crassostrea - drug effects Crassostrea - physiology Crassostrea gigas Detoxification Digestive glands Earth and Environmental Science Ecotoxicology Environment Environmental Chemistry Environmental Health Environmental science Excretion Exposure Gills Gonads Invertebrate Zoology Kinetics Laboratories Life Sciences Lipids Mantle Marine organisms Metals Mollusks Morphology Multi-Stressors in Freshwater and Transitional Environments: from Legacy Pollutants to Emerging Ones Muscles Organisms Organotropism Organs Oysters Physiology Platinum Platinum - toxicity Pollutants Seawater Seawater - chemistry Shellfish Time dependence Toxicology Trace elements Tropism - drug effects Waste Water Technology Water Management Water Pollutants, Chemical - toxicity Water Pollution Control |
| title | Organotropism and biomarker response in oyster Crassostrea gigas exposed to platinum in seawater |
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