Management of bleeding peptic duodenal ulcer refractory to endoscopic treatment: surgery or transcatheter arterial embolization as first-line therapy? A retrospective single-center study and systematic review
Background The objective of this study was to compare the results of transcatheter arterial embolization ( TAE) with surgery in terms of efficacy in the context of bleeding duodenal ulcer (BDU) refractory to endoscopic treatment. Materials and methods From January 2006 to December 2016, all patients...
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| Veröffentlicht in: | European journal of trauma and emergency surgery (Munich : 2007) 2020-10, Vol.46 (5), p.1025-1035 |
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| creator | Darmon, Ilan Rebibo, Lionel Diouf, Momar Chivot, Cyril Riault, Clémentine Yzet, Thierry Le Mouel, Jean Philippe Regimbeau, Jean-Marc |
| description | Background
The objective of this study was to compare the results of transcatheter arterial embolization
(
TAE) with surgery in terms of efficacy in the context of bleeding duodenal ulcer (BDU) refractory to endoscopic treatment.
Materials and methods
From January 2006 to December 2016, all patients treated for a BDU refractory to endoscopic treatment were included in this observational, comparative, retrospective, single-center study. Primary endpoint was the overall success of treatment of BDU requiring surgical and/or TAE. The secondary endpoints were pre-interventional data, recurrence rates, feasibility of secondary treatment, morbidity and mortality of surgical and radiological treatment, intensive care unit and length of stay. A systematic review of the literature was performed to compare results of surgery and TAE.
Results
59 out of 396 patients (14.9%) treated for BDU required embolization and/or surgery: 15 patients underwent surgery (group S) including 7 patients after embolization failure and 44 patients underwent TAE (group TAE). The overall treatment success in intention to treat (85.7% vs 67.3%), per protocol (80% vs 79.5%) and bleeding recurrence rates (20% vs 15.9%) were also identical. Mortality (14.2% vs 15.3%) was similar between the two groups. Our study data were pooled with data from eight published studies and suggest that surgery have significant increased overall success (68.3% vs. 55.4%,
p
|
| doi_str_mv | 10.1007/s00068-020-01356-7 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_hal_p</sourceid><recordid>TN_cdi_hal_primary_oai_HAL_hal_03595655v1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2386289342</sourcerecordid><originalsourceid>FETCH-LOGICAL-c409t-568a2f5a0b12d0b26c5411ee1ce751a37c455fc5c6502ec17e7ff52c94b12f923</originalsourceid><addsrcrecordid>eNp9ksuO1DAQRSMEYh7wAyyQJTawCPgROwkb1BoxDFIjNrC2HKfS41FiB9tp1Hwln0SFHhqJBRvbss-9VXLdonjG6GtGaf0mUUpVU1JOS8qEVGX9oDhnjRJl21bs4eksxFlxkdId0lRJ_rg4E5xXiqn2vPj5yXizgwl8JmEg3QjQO78jM8zZWdIvoQdvRrKMFiKJMERjc4gHkgMB34dkw4xcjmDyavKWpCXuAIEQ8db4ZE2-hYxiE3F16AVTF0b3w2QXPDGJDC6mXI7OA0E0mvnwjmywVo4hzWCz2wNJ2NQIpcUSaJXy0h-I8T1Jh5RhMmuvEfYOvj8pHg1mTPD0fr8svl6__3J1U24_f_h4tdmWtqJtLqVqDB-koR3jPe24srJiDIBZqCUzoraVlIOVVknKwbIa6mGQ3LYVCoaWi8vi1dH31ox6jm4y8aCDcfpms9XrHRWylUrKPUP25ZGdY_i2QMp6csnCOBoPYUmai0bxphXVavviH_QuLBEngFRVs5rKVq0UP1IWvyjhVE4dMKrXbOhjNjRmQ__Ohq5R9Pzeeukm6E-SP2FAQByBhE8eh_i39n9sfwE-98mv</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2471705962</pqid></control><display><type>article</type><title>Management of bleeding peptic duodenal ulcer refractory to endoscopic treatment: surgery or transcatheter arterial embolization as first-line therapy? A retrospective single-center study and systematic review</title><source>MEDLINE</source><source>Springer Nature - Complete Springer Journals</source><creator>Darmon, Ilan ; Rebibo, Lionel ; Diouf, Momar ; Chivot, Cyril ; Riault, Clémentine ; Yzet, Thierry ; Le Mouel, Jean Philippe ; Regimbeau, Jean-Marc</creator><creatorcontrib>Darmon, Ilan ; Rebibo, Lionel ; Diouf, Momar ; Chivot, Cyril ; Riault, Clémentine ; Yzet, Thierry ; Le Mouel, Jean Philippe ; Regimbeau, Jean-Marc</creatorcontrib><description>Background
The objective of this study was to compare the results of transcatheter arterial embolization
(
TAE) with surgery in terms of efficacy in the context of bleeding duodenal ulcer (BDU) refractory to endoscopic treatment.
Materials and methods
From January 2006 to December 2016, all patients treated for a BDU refractory to endoscopic treatment were included in this observational, comparative, retrospective, single-center study. Primary endpoint was the overall success of treatment of BDU requiring surgical and/or TAE. The secondary endpoints were pre-interventional data, recurrence rates, feasibility of secondary treatment, morbidity and mortality of surgical and radiological treatment, intensive care unit and length of stay. A systematic review of the literature was performed to compare results of surgery and TAE.
Results
59 out of 396 patients (14.9%) treated for BDU required embolization and/or surgery: 15 patients underwent surgery (group S) including 7 patients after embolization failure and 44 patients underwent TAE (group TAE). The overall treatment success in intention to treat (85.7% vs 67.3%), per protocol (80% vs 79.5%) and bleeding recurrence rates (20% vs 15.9%) were also identical. Mortality (14.2% vs 15.3%) was similar between the two groups. Our study data were pooled with data from eight published studies and suggest that surgery have significant increased overall success (68.3% vs. 55.4%,
p
< 0.005).
Conclusion
The overall success rate was in favour of surgery according our meta-analysis. Our single-center study highlights the fact that predictive factors for recurrent bleeding after TAE must be identified to select good candidates for TAE and/or surgery.</description><identifier>ISSN: 1863-9933</identifier><identifier>EISSN: 1863-9941</identifier><identifier>DOI: 10.1007/s00068-020-01356-7</identifier><identifier>PMID: 32246169</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Angiography ; Critical Care - statistics & numerical data ; Critical Care Medicine ; Embolization ; Embolization, Therapeutic - methods ; Emergency medical care ; Emergency Medicine ; Endoscopy ; Endoscopy, Gastrointestinal ; Female ; Humans ; Intensive ; Length of Stay - statistics & numerical data ; Life Sciences ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Original Article ; Peptic Ulcer Hemorrhage - diagnostic imaging ; Peptic Ulcer Hemorrhage - mortality ; Peptic Ulcer Hemorrhage - therapy ; Recurrence ; Retrospective Studies ; Risk Factors ; Sports Medicine ; Success ; Surgery ; Surgical Orthopedics ; Systematic review ; Traumatic Surgery ; Ulcers</subject><ispartof>European journal of trauma and emergency surgery (Munich : 2007), 2020-10, Vol.46 (5), p.1025-1035</ispartof><rights>Springer-Verlag GmbH Germany, part of Springer Nature 2020</rights><rights>Springer-Verlag GmbH Germany, part of Springer Nature 2020.</rights><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c409t-568a2f5a0b12d0b26c5411ee1ce751a37c455fc5c6502ec17e7ff52c94b12f923</citedby><cites>FETCH-LOGICAL-c409t-568a2f5a0b12d0b26c5411ee1ce751a37c455fc5c6502ec17e7ff52c94b12f923</cites><orcidid>0000-0001-7631-9112 ; 0000-0002-1372-3182 ; 0000-0002-1829-1200 ; 0000-0001-9528-2669 ; 0000-0002-5245-4456 ; 0000-0001-9908-8265</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00068-020-01356-7$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00068-020-01356-7$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>230,314,776,780,881,27903,27904,41467,42536,51297</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32246169$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://u-picardie.hal.science/hal-03595655$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Darmon, Ilan</creatorcontrib><creatorcontrib>Rebibo, Lionel</creatorcontrib><creatorcontrib>Diouf, Momar</creatorcontrib><creatorcontrib>Chivot, Cyril</creatorcontrib><creatorcontrib>Riault, Clémentine</creatorcontrib><creatorcontrib>Yzet, Thierry</creatorcontrib><creatorcontrib>Le Mouel, Jean Philippe</creatorcontrib><creatorcontrib>Regimbeau, Jean-Marc</creatorcontrib><title>Management of bleeding peptic duodenal ulcer refractory to endoscopic treatment: surgery or transcatheter arterial embolization as first-line therapy? A retrospective single-center study and systematic review</title><title>European journal of trauma and emergency surgery (Munich : 2007)</title><addtitle>Eur J Trauma Emerg Surg</addtitle><addtitle>Eur J Trauma Emerg Surg</addtitle><description>Background
The objective of this study was to compare the results of transcatheter arterial embolization
(
TAE) with surgery in terms of efficacy in the context of bleeding duodenal ulcer (BDU) refractory to endoscopic treatment.
Materials and methods
From January 2006 to December 2016, all patients treated for a BDU refractory to endoscopic treatment were included in this observational, comparative, retrospective, single-center study. Primary endpoint was the overall success of treatment of BDU requiring surgical and/or TAE. The secondary endpoints were pre-interventional data, recurrence rates, feasibility of secondary treatment, morbidity and mortality of surgical and radiological treatment, intensive care unit and length of stay. A systematic review of the literature was performed to compare results of surgery and TAE.
Results
59 out of 396 patients (14.9%) treated for BDU required embolization and/or surgery: 15 patients underwent surgery (group S) including 7 patients after embolization failure and 44 patients underwent TAE (group TAE). The overall treatment success in intention to treat (85.7% vs 67.3%), per protocol (80% vs 79.5%) and bleeding recurrence rates (20% vs 15.9%) were also identical. Mortality (14.2% vs 15.3%) was similar between the two groups. Our study data were pooled with data from eight published studies and suggest that surgery have significant increased overall success (68.3% vs. 55.4%,
p
< 0.005).
Conclusion
The overall success rate was in favour of surgery according our meta-analysis. Our single-center study highlights the fact that predictive factors for recurrent bleeding after TAE must be identified to select good candidates for TAE and/or surgery.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Angiography</subject><subject>Critical Care - statistics & numerical data</subject><subject>Critical Care Medicine</subject><subject>Embolization</subject><subject>Embolization, Therapeutic - methods</subject><subject>Emergency medical care</subject><subject>Emergency Medicine</subject><subject>Endoscopy</subject><subject>Endoscopy, Gastrointestinal</subject><subject>Female</subject><subject>Humans</subject><subject>Intensive</subject><subject>Length of Stay - statistics & numerical data</subject><subject>Life Sciences</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Original Article</subject><subject>Peptic Ulcer Hemorrhage - diagnostic imaging</subject><subject>Peptic Ulcer Hemorrhage - mortality</subject><subject>Peptic Ulcer Hemorrhage - therapy</subject><subject>Recurrence</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Sports Medicine</subject><subject>Success</subject><subject>Surgery</subject><subject>Surgical Orthopedics</subject><subject>Systematic review</subject><subject>Traumatic Surgery</subject><subject>Ulcers</subject><issn>1863-9933</issn><issn>1863-9941</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp9ksuO1DAQRSMEYh7wAyyQJTawCPgROwkb1BoxDFIjNrC2HKfS41FiB9tp1Hwln0SFHhqJBRvbss-9VXLdonjG6GtGaf0mUUpVU1JOS8qEVGX9oDhnjRJl21bs4eksxFlxkdId0lRJ_rg4E5xXiqn2vPj5yXizgwl8JmEg3QjQO78jM8zZWdIvoQdvRrKMFiKJMERjc4gHkgMB34dkw4xcjmDyavKWpCXuAIEQ8db4ZE2-hYxiE3F16AVTF0b3w2QXPDGJDC6mXI7OA0E0mvnwjmywVo4hzWCz2wNJ2NQIpcUSaJXy0h-I8T1Jh5RhMmuvEfYOvj8pHg1mTPD0fr8svl6__3J1U24_f_h4tdmWtqJtLqVqDB-koR3jPe24srJiDIBZqCUzoraVlIOVVknKwbIa6mGQ3LYVCoaWi8vi1dH31ox6jm4y8aCDcfpms9XrHRWylUrKPUP25ZGdY_i2QMp6csnCOBoPYUmai0bxphXVavviH_QuLBEngFRVs5rKVq0UP1IWvyjhVE4dMKrXbOhjNjRmQ__Ohq5R9Pzeeukm6E-SP2FAQByBhE8eh_i39n9sfwE-98mv</recordid><startdate>20201001</startdate><enddate>20201001</enddate><creator>Darmon, Ilan</creator><creator>Rebibo, Lionel</creator><creator>Diouf, Momar</creator><creator>Chivot, Cyril</creator><creator>Riault, Clémentine</creator><creator>Yzet, Thierry</creator><creator>Le Mouel, Jean Philippe</creator><creator>Regimbeau, Jean-Marc</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><general>Springer Verlag</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>1XC</scope><orcidid>https://orcid.org/0000-0001-7631-9112</orcidid><orcidid>https://orcid.org/0000-0002-1372-3182</orcidid><orcidid>https://orcid.org/0000-0002-1829-1200</orcidid><orcidid>https://orcid.org/0000-0001-9528-2669</orcidid><orcidid>https://orcid.org/0000-0002-5245-4456</orcidid><orcidid>https://orcid.org/0000-0001-9908-8265</orcidid></search><sort><creationdate>20201001</creationdate><title>Management of bleeding peptic duodenal ulcer refractory to endoscopic treatment: surgery or transcatheter arterial embolization as first-line therapy? A retrospective single-center study and systematic review</title><author>Darmon, Ilan ; Rebibo, Lionel ; Diouf, Momar ; Chivot, Cyril ; Riault, Clémentine ; Yzet, Thierry ; Le Mouel, Jean Philippe ; Regimbeau, Jean-Marc</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c409t-568a2f5a0b12d0b26c5411ee1ce751a37c455fc5c6502ec17e7ff52c94b12f923</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Angiography</topic><topic>Critical Care - statistics & numerical data</topic><topic>Critical Care Medicine</topic><topic>Embolization</topic><topic>Embolization, Therapeutic - methods</topic><topic>Emergency medical care</topic><topic>Emergency Medicine</topic><topic>Endoscopy</topic><topic>Endoscopy, Gastrointestinal</topic><topic>Female</topic><topic>Humans</topic><topic>Intensive</topic><topic>Length of Stay - statistics & numerical data</topic><topic>Life Sciences</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Original Article</topic><topic>Peptic Ulcer Hemorrhage - diagnostic imaging</topic><topic>Peptic Ulcer Hemorrhage - mortality</topic><topic>Peptic Ulcer Hemorrhage - therapy</topic><topic>Recurrence</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Sports Medicine</topic><topic>Success</topic><topic>Surgery</topic><topic>Surgical Orthopedics</topic><topic>Systematic review</topic><topic>Traumatic Surgery</topic><topic>Ulcers</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Darmon, Ilan</creatorcontrib><creatorcontrib>Rebibo, Lionel</creatorcontrib><creatorcontrib>Diouf, Momar</creatorcontrib><creatorcontrib>Chivot, Cyril</creatorcontrib><creatorcontrib>Riault, Clémentine</creatorcontrib><creatorcontrib>Yzet, Thierry</creatorcontrib><creatorcontrib>Le Mouel, Jean Philippe</creatorcontrib><creatorcontrib>Regimbeau, Jean-Marc</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>Hyper Article en Ligne (HAL)</collection><jtitle>European journal of trauma and emergency surgery (Munich : 2007)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Darmon, Ilan</au><au>Rebibo, Lionel</au><au>Diouf, Momar</au><au>Chivot, Cyril</au><au>Riault, Clémentine</au><au>Yzet, Thierry</au><au>Le Mouel, Jean Philippe</au><au>Regimbeau, Jean-Marc</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Management of bleeding peptic duodenal ulcer refractory to endoscopic treatment: surgery or transcatheter arterial embolization as first-line therapy? A retrospective single-center study and systematic review</atitle><jtitle>European journal of trauma and emergency surgery (Munich : 2007)</jtitle><stitle>Eur J Trauma Emerg Surg</stitle><addtitle>Eur J Trauma Emerg Surg</addtitle><date>2020-10-01</date><risdate>2020</risdate><volume>46</volume><issue>5</issue><spage>1025</spage><epage>1035</epage><pages>1025-1035</pages><issn>1863-9933</issn><eissn>1863-9941</eissn><abstract>Background
The objective of this study was to compare the results of transcatheter arterial embolization
(
TAE) with surgery in terms of efficacy in the context of bleeding duodenal ulcer (BDU) refractory to endoscopic treatment.
Materials and methods
From January 2006 to December 2016, all patients treated for a BDU refractory to endoscopic treatment were included in this observational, comparative, retrospective, single-center study. Primary endpoint was the overall success of treatment of BDU requiring surgical and/or TAE. The secondary endpoints were pre-interventional data, recurrence rates, feasibility of secondary treatment, morbidity and mortality of surgical and radiological treatment, intensive care unit and length of stay. A systematic review of the literature was performed to compare results of surgery and TAE.
Results
59 out of 396 patients (14.9%) treated for BDU required embolization and/or surgery: 15 patients underwent surgery (group S) including 7 patients after embolization failure and 44 patients underwent TAE (group TAE). The overall treatment success in intention to treat (85.7% vs 67.3%), per protocol (80% vs 79.5%) and bleeding recurrence rates (20% vs 15.9%) were also identical. Mortality (14.2% vs 15.3%) was similar between the two groups. Our study data were pooled with data from eight published studies and suggest that surgery have significant increased overall success (68.3% vs. 55.4%,
p
< 0.005).
Conclusion
The overall success rate was in favour of surgery according our meta-analysis. Our single-center study highlights the fact that predictive factors for recurrent bleeding after TAE must be identified to select good candidates for TAE and/or surgery.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>32246169</pmid><doi>10.1007/s00068-020-01356-7</doi><tpages>11</tpages><orcidid>https://orcid.org/0000-0001-7631-9112</orcidid><orcidid>https://orcid.org/0000-0002-1372-3182</orcidid><orcidid>https://orcid.org/0000-0002-1829-1200</orcidid><orcidid>https://orcid.org/0000-0001-9528-2669</orcidid><orcidid>https://orcid.org/0000-0002-5245-4456</orcidid><orcidid>https://orcid.org/0000-0001-9908-8265</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1863-9933 |
| ispartof | European journal of trauma and emergency surgery (Munich : 2007), 2020-10, Vol.46 (5), p.1025-1035 |
| issn | 1863-9933 1863-9941 |
| language | eng |
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| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Adult Aged Aged, 80 and over Angiography Critical Care - statistics & numerical data Critical Care Medicine Embolization Embolization, Therapeutic - methods Emergency medical care Emergency Medicine Endoscopy Endoscopy, Gastrointestinal Female Humans Intensive Length of Stay - statistics & numerical data Life Sciences Male Medicine Medicine & Public Health Middle Aged Original Article Peptic Ulcer Hemorrhage - diagnostic imaging Peptic Ulcer Hemorrhage - mortality Peptic Ulcer Hemorrhage - therapy Recurrence Retrospective Studies Risk Factors Sports Medicine Success Surgery Surgical Orthopedics Systematic review Traumatic Surgery Ulcers |
| title | Management of bleeding peptic duodenal ulcer refractory to endoscopic treatment: surgery or transcatheter arterial embolization as first-line therapy? A retrospective single-center study and systematic review |
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