Does the Administration of Sevelamer or Nicotinamide Modify Uremic Toxins or Endotoxemia in Chronic Hemodialysis Patients?

Background Hyperphosphatemia control is a major issue in hemodialysis patients. Both sevelamer and nicotinamide are prescribed for this purpose. In addition, they exert pleiotropic effects such as an improvement of inflammatory status and potentially enhanced clearance of uremic toxins. In the prese...

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Veröffentlicht in:	Drugs (New York, N.Y.) N.Y.), 2019-06, Vol.79 (8), p.855-862
Hauptverfasser:	Lenglet, Aurelie, Fabresse, Nicolas, Taupin, Méline, Gomila, Cathy, Liabeuf, Sophie, Kamel, Said, Alvarez, Jean Claude, Drueke, Tilman B., Massy, Ziad A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetic acid C-reactive protein Cardiovascular disease Cardiovascular diseases Clinical outcomes Cytokines Diabetes mellitus Dialysis Endotoxemia Endotoxins Enzyme-linked immunosorbent assay Enzymes Fibroblast growth factors Fibroblasts Growth factors Hemodialysis Hippuric acid Hyperphosphatemia Indoleacetic acid Inflammation Internal Medicine Kidney diseases Kynurenic acid Life Sciences Lipopolysaccharides Liquid chromatography Low molecular weights Mass spectrometry Mass spectroscopy Medicine Medicine & Public Health Microbiota Mortality NADPH Nicotinamide Original Research Article Parathyroid Parathyroid hormone Pharmacology/Toxicology Pharmacotherapy Phosphates Precursors Proteins Secondary analysis Serum levels Signal transduction Sulfates Toxins Trimethylamine Trimethylamine-N-oxide Urea Ureas Uric acid
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