Can Heterocyclic γ‐Peptides Provide Polyfunctional Platforms for Synthetic Glycocluster Construction?

Sugars play key roles in many molecular and cellular communication processes involving a family of proteins named lectins. The low affinity associated with sugar recognition is generally counterbalanced by the multivalent nature of the interaction. While many polyglycosylated architectures have been...

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Veröffentlicht in:	Chemistry : a European journal 2018-08, Vol.24 (44), p.11426-11432
Hauptverfasser:	Simon, Matthieu, Ali, Lamiaa M. A., El Cheikh, Khaled, Aguesseau, Julie, Gary‐Bobo, Magali, Garcia, Marcel, Morère, Alain, Maillard, Ludovic T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids cell chemistry Cellular communication Chemical Sciences Chemistry foldamers glycoclusters Lectins Oligomers Peptides Proteins Sugar Therapeutic applications Topology
Online-Zugang:	Volltext
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