Renin‐angiotensin system is involved in embryonic emergence of hematopoietic stem/progenitor cells

Angiotensin‐converting enzyme (ACE), a key element of the renin‐angiotensin system (RAS), has recently been identified as a new marker of both adult and embryonic human hematopoietic stem/progenitor cells (HSPCs). However, whether a full renin‐angiotensin pathway is locally present during the hemato...

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Veröffentlicht in:	Stem cells (Dayton, Ohio) Ohio), 2021-05, Vol.39 (5), p.636-649
Hauptverfasser:	Julien, Emmanuelle, Biasch, Katia, El Omar, Reine, Freund, Jean‐Noël, Gachet, Christian, Lanza, François, Tavian, Manuela
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin AT1 receptors Angiotensin II Angiotensinogen angiotensin‐converting enzyme Aorta Autocrine signalling CD45 antigen Cell culture Cells (biology) embryo Embryogenesis Embryonic growth stage Embryos Enzymes Hematopoiesis Hematopoietic stem cells hematopoietic stem progenitor cell hemogenic endothelium Life Sciences Localization Paracrine signalling Perturbation Progenitor cells Receptors Renin renin‐angiotensin system Splanchnopleura
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