MALDI-TOF mass spectrometric analysis for the characterization of the 5,10,15,20-tetrakis- (m-hydroxyphenyl)bacteriochlorin (m-THPBC) photoproducts in biological environment

Photoproducts formation upon irradiation (739 nm) of 5,10,15,20‐tetrakis(m‐hydroxyphenyl)bacteriochlorin (m‐THPBC) in phosphate buffer saline (PBS) supplemented with human serum albumin (HSA) were studied by means of absorption spectroscopy and MALDI‐TOF mass spectrometry. The experiments were perfo...

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Veröffentlicht in:	Journal of mass spectrometry. 2005-09, Vol.40 (9), p.1149-1156
Hauptverfasser:	Lassalle, Henri-Pierre, Lourette, Natacha, Maunit, Benoît, Muller, Jean-François, Guillemin, François, Bezdetnaya-Bolotine, Lina
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cancer Environmental Monitoring - methods Humans Life Sciences Light m-THPBC MALDI-TOF-MS mass spectrometry Medical sciences Photobleaching Photochemotherapy photodynamic therapy photoproducts formation Photoradiation therapy and photosensitizing agent Porphyrins - chemistry Porphyrins - radiation effects Radiation-Sensitizing Agents - chemistry Radiation-Sensitizing Agents - radiation effects Serum Albumin - chemistry Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods Treatment with physical agents Treatment. General aspects Tumors
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