BP180-specific IgG is associated with skin adverse events, therapy response, and overall survival in non-small cell lung cancer patients treated with checkpoint inhibitors

Anti-programmed cell death protein 1 (PD1)/programmed death-ligand 1(PD-L1) therapy frequently entails immune-related adverse events (irAEs), and biomarkers to predict irAEs are lacking. Although checkpoint inhibitors have been found to reinvigorate T cells, the relevance of autoantibodies remains e...

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Veröffentlicht in:Journal of the American Academy of Dermatology 2020-04, Vol.82 (4), p.854-861
Hauptverfasser: Hasan Ali, Omar, Bomze, David, Ring, Sandra S., Berner, Fiamma, Fässler, Mirjam, Diem, Stefan, Abdou, Marie-Therese, Hammers, Christoph, Emtenani, Shirin, Braun, Anne, Cozzio, Antonio, Mani, Bernhard, Jochum, Wolfram, Schmidt, Enno, Zillikens, Detlef, Sadik, Christian D., Flatz, Lukas
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Sprache:eng
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