Endogenous Mas‐related G‐protein‐coupled receptor X1 activates and sensitizes TRPA1 in a human model of peripheral nerves

Mas‐related G‐protein‐coupled receptor X1 (MrgprX1) is a human‐specific Mrgpr and its expression is restricted to primary sensory neurons. However, its role in nociception and pain signaling pathways is largely unknown. This study aims to investigate a role for MrgprX1 in nociception via interaction...

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