Design of polyurea networks containing anticancer and anti‐inflammatory drugs for dual drug delivery purposes

Naproxen (Nap), a non‐steroidal anti‐inflammatory drug, and 5‐fluorouracil (5FU), an anticancer drug, were easily incorporated into a polyurea xerogel. Polyureas (PUr) were synthesized by one pot reaction via sol–gel chemistry. Soft segments were based on polyetheramine‐PEO and hard segments were ba...

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Veröffentlicht in:	Journal of applied polymer science 2022-04, Vol.139 (16), p.n/a
Hauptverfasser:	Resende, Mariane A., Pedroza, Gabriele A., Macêdo, Lucia H. G. M. C., Oliveira, Ricardo, Amela‐Cortes, Maria, Molard, Yann, Molina, Eduardo F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amines Cancer Chain mobility Chemical compounds Chemical Sciences Contact lenses Differential scanning calorimetry drug delivery systems Drugs elastomers Fourier transforms glass transition Hexamethylene diisocyanate Infrared spectroscopy Materials science Naproxen Pharmacology polyetheramine Polyethers Polymers Polyureas Segments Small angle X ray scattering Sol-gel processes Solvation spectroscopy Trimers Xerogels
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