Fibroblast heterogeneity in tumor micro-environment: Role in immunosuppression and new therapies

•CAFs exhibit a phenotypic heterogeneity that define their functions in tumors.•Different CAF subsets are associated with an immunosuppressive microenvironment.•CAFs immunosuppressive functions act on both innate and adaptive immune response.•CAFs emerge as an attractive target for the development o...

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Veröffentlicht in:	Seminars in immunology 2020-04, Vol.48, p.101417-101417, Article 101417
Hauptverfasser:	Mhaidly, Rana, Mechta-Grigoriou, Fatima
Format:	Artikel
Sprache:	eng
Schlagworte:	CAF Cancer Cancer associated fibroblasts Immunosuppression Life Sciences Macrophages Stroma T lymphocytes Tumor microenvironment
Online-Zugang:	Volltext
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