Increased microglial activation in patients with Parkinson disease using [$^{18}$F]-DPA714 TSPO PET imaging

Introduction: Increasing evidence suggests that neuroinflammation is active in Parkinson disease (PD) and contributes to neurodegeneration. This process can be studied in vivo with PET and radioligands targeting TSPO, upregulated in activated microglia. Initial PET studies investigating microglial a...

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Veröffentlicht in:	Parkinsonism & related disorders 2021-01, Vol.82, p.29-36
Hauptverfasser:	Lavisse, Sonia, Goutal, Sébastien, Wimberley, Catriona, Tonietto, Mattéo, Bottlaender, Michel, Gervais, Philippe, Kuhnast, Bertrand, Peyronneau, Marie-Anne, Barret, Olivier, Lagarde, Julien, Sarazin, Marie, Hantraye, Philippe, Thiriez, Claire, Remy, Philippe
Format:	Artikel
Sprache:	eng
Schlagworte:	Life Sciences
Online-Zugang:	Volltext
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