Synthesis of High-Mannose Oligosaccharide Analogues through Click Chemistry: True Functional Mimics of Their Natural Counterparts Against Lectins?

Terminal “high‐mannose oligosaccharides” are involved in a broad range of biological and pathological processes, from sperm‐egg fusion to influenza and human immunodeficiency virus infections. In spite of many efforts, their synthesis continues to be very challenging and actually represents a major...

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Veröffentlicht in:Chemistry : a European journal 2015-01, Vol.21 (5), p.1978-1991
Hauptverfasser: François-Heude, Marc, Méndez-Ardoy, Alejandro, Cendret, Virginie, Lafite, Pierre, Daniellou, Richard, Ortiz Mellet, Carmen, García Fernández, José M., Moreau, Vincent, Djedaïni-Pilard, Florence
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Sprache:eng
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