An Update on Direct Genotoxicity as a Molecular Mechanism of Ochratoxin A Carcinogenicity

Ochratoxin A (OTA) is a naturally occurring chlorophenolic fungal toxin that contaminates a wide range of food products and poses a cancer threat to humans. The mechanism of action (MOA) for OTA renal carcinogenicity is a controversial issue. In 2005, direct genotoxicity (covalent DNA adduct formati...

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Veröffentlicht in:	Chemical research in toxicology 2012-02, Vol.25 (2), p.252-262
Hauptverfasser:	Pfohl-Leszkowicz, Annie, Manderville, Richard A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cancer Carcinogens - toxicity DNA Adducts Humans Life Sciences Mitosis - drug effects Mutagens - toxicity Mycotoxins - toxicity Ochratoxins - toxicity Oxidative Stress - drug effects Toxicology Toxicology and food chain Vegetal toxicology and mycotoxicology
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