Pinstripe: a suite of programs for integrating transcriptomic and proteomic datasets identifies novel proteins and improves differentiation of protein-coding and non-coding genes

Comparing transcriptomic data with proteomic data to identify protein-coding sequences is a long-standing challenge in molecular biology, one that is exacerbated by the increasing size of high-throughput datasets. To address this challenge, and thereby to improve the quality of genome annotation and...

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Veröffentlicht in:	Bioinformatics 2012-12, Vol.28 (23), p.3042-3050
Hauptverfasser:	GASCOIGNE, Dennis K, CHEETHAM, Seth W, CATTENOZ, Pierre B, CLARK, Michael B, AMARAL, Paulo P, TAFT, Ryan J, WILHELM, Dagmar, DINGER, Marcel E, MATTICK, John S
Format:	Artikel
Sprache:	eng
Schlagworte:	Annotations Bioinformatics Biological and medical sciences Computational Biology Computational Biology - methods Databases, Protein Exons Fundamental and applied biological sciences. Psychology Gene Expression Profiling Gene Expression Profiling - methods Gene Library General aspects Genes Genome Genomes Genomics Genomics - methods Humans Life Sciences Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects) Molecular Sequence Annotation Open Reading Frames Peptides Proteins Proteins - genetics Proteomics Proteomics - methods Quantitative Methods RNA, Long Noncoding RNA, Long Noncoding - genetics RNA, Messenger RNA, Messenger - genetics Sequence Analysis, RNA Software Translations
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