Joint involvement in Noonan syndrome. A retrospective paediatric descriptive study

•In Noonan syndrome, joint symptoms appear during childhood.•Musculoskeletal pain are present in 25 % of the patients and joint stiffness in 14 %.•The knees and the elbows, are the more affected joints.•Treatment with GH and SOS1 mutations was significantly related to the occurrence of musculoskelet...

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Veröffentlicht in:	Joint, bone, spine : revue du rhumatisme bone, spine : revue du rhumatisme, 2022-01, Vol.89 (1), p.105270-105270, Article 105270
Hauptverfasser:	Le Quellec, Aurore, Edouard, Thomas, Audebert-Bellanger, Séverine, Pouzet, Antoine, Bourdet, Karine, Colson, Cindy, Oriot, Charlotte, Poignant, Sylvaine, Saraux, Alain, Devauchelle-Pensec, Valérie
Format:	Artikel
Sprache:	eng
Schlagworte:	Central giant cell granuloma Immunology Joint involvement Life Sciences Noonan Syndrome Pigmented villonodular synovitis RASopathy
Online-Zugang:	Volltext
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