Pharmacological validation of Solanum mammosum L. as an anti-infective agent: Role of solamargine

Fungal and bacterial infections remain a major problem worldwide, requiring the development of effective therapeutic strategies. Solanum mammosum L. (Solanaceae) (“teta de vaca”) is used in traditional medicine in Peru to treat fungal infections and respiratory disorders via topical application. How...

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Veröffentlicht in:	Journal of ethnopharmacology 2021-11, Vol.280, p.114473-114473, Article 114473
Hauptverfasser:	Cabanillas, Billy, Chassagne, François, Vásquez-Ocmín, Pedro, Tahrioui, Ali, Chevalier, Sylvie, Vansteelandt, Marieke, Triastuti, Asih, Amasifuen Guerra, Carlos A., Fabre, Nicolas, Haddad, Mohamed
Format:	Artikel
Sprache:	eng
Schlagworte:	active ingredients Anti-Bacterial Agents - isolation & purification Anti-Bacterial Agents - pharmacology Antifungal Agents - isolation & purification Antifungal Agents - pharmacology antifungal properties Arthrodermataceae - drug effects Bioautography biofilm Biofilms - drug effects Candida albicans Candida albicans - drug effects fruits fungi LC-HRMS Life Sciences mechanism of action metabolites Microbial Sensitivity Tests minimum inhibitory concentration Peru Plant Extracts - chemistry Plant Extracts - isolation & purification Plant Extracts - pharmacology Pseudomonas aeruginosa Pseudomonas aeruginosa - drug effects pyocyanin Pyocyanine - metabolism Solamargine Solanaceous Alkaloids - isolation & purification Solanaceous Alkaloids - pharmacology Solanum - chemistry Solanum mammosum topical application traditional medicine Trichophyton mentagrophytes
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