Novel G-quadruplex prone sequences emerge in the complete assembly of the human X chromosome

G-quadruplexes are non-B secondary structures with regulatory functions and therapeutic potential. Improvements in sequencing methods recently allowed the completion of the first human chromosome which is now available as a gapless, end-to-end assembly, with the previously remaining spaces filled an...

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Veröffentlicht in:	Biochimie 2021-12, Vol.191, p.87-90
Hauptverfasser:	Bohálová, Natália, Mergny, Jean-Louis, Brázda, Václav
Format:	Artikel
Sprache:	eng
Schlagworte:	Bioinformatics Chromosome X Chromosomes, Human, X - chemistry Chromosomes, Human, X - genetics G-quadruplex G-Quadruplexes G4Hunter Humans Life Sciences Non-B DNA Quantitative Methods
Online-Zugang:	Volltext
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