Redox Properties of the Membrane Proteins from the Respiratory Chain

This review focuses on the electrochemical and spectroelectrochemical studies that gave insight into redox potentials of the four mitochondrial complexes and their homologues from bacterial respiratory chains using O2 as a terminal acceptor, thus providing crucial information about their reaction me...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Chemical reviews 2020-09, Vol.120 (18), p.10244-10297
Hauptverfasser:	Melin, Frederic, Hellwig, Petra
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptation Chains Chemical Sciences Corrosion inhibitors Electrochemistry Enzymes Homology Membranes Other Proteins Quinones Reaction mechanisms Substrate inhibition Substrates
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

container_end_page	10297
container_issue	18
container_start_page	10244
container_title	Chemical reviews
container_volume	120
creator	Melin, Frederic Hellwig, Petra
description	This review focuses on the electrochemical and spectroelectrochemical studies that gave insight into redox potentials of the four mitochondrial complexes and their homologues from bacterial respiratory chains using O2 as a terminal acceptor, thus providing crucial information about their reaction mechanism. Advantages and limitations of the use of the different techniques for the study of membrane proteins are presented. Electrocatalytic experiments are described that revealed specific features of the reaction with the substrates and inhibitors. An overview is given on the great variability of the redox and catalytic properties of the enzymes in different organisms that may be due to adaptation to the specific environments in which these enzymes function. The adaptation of the redox chain to the different types of quinone and substrates is analyzed, and future studies are discussed.
doi_str_mv	10.1021/acs.chemrev.0c00249
format	Article
fullrecord	<record><control><sourceid>proquest_hal_p</sourceid><recordid>TN_cdi_hal_primary_oai_HAL_hal_03341539v1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2447948797</sourcerecordid><originalsourceid>FETCH-LOGICAL-a473t-457d4329eb1504778e53963defae7cfe243968e2660e8028dff5e18cdd3f4aff3</originalsourceid><addsrcrecordid>eNp9kctKAzEUhoMoWi9PIMiAG11MzXWSLKVeoaIUXYd05oRO6TQ1mRb79mZs7cKFq3ByvvOfy4_QOcF9gim5sWXslxNoAqz6uMSYcr2HekRQnBdK433UwxjrnBaFOELHMU5TKASVh-iIUUWx0qyH7kZQ-a_sLfgFhLaGmHmXtRPIXqAZBzuHLtVCPY-ZC775SY0gLupgWx_W2WBi6_kpOnB2FuFs-56gj4f798FTPnx9fB7cDnPLJWtzLmTFGdUwJgJzKRUIpgtWgbMgSweUp1BBGhiDwlRVzgkgqqwq5rh1jp2g643uxM7MItSNDWvjbW2eboem-8OMcZJEVySxVxt2EfznEmJrmjqWMJulnfwymtSsYFqkoyX08g869cswT5skikvNldQyUWxDlcHHGMDtJiDYdIaYZIjZGmK2hqSqi632ctxAtav5dSABNxugq971_U_yGy3Cl68</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2447948797</pqid></control><display><type>article</type><title>Redox Properties of the Membrane Proteins from the Respiratory Chain</title><source>American Chemical Society Journals</source><creator>Melin, Frederic ; Hellwig, Petra</creator><creatorcontrib>Melin, Frederic ; Hellwig, Petra</creatorcontrib><description>This review focuses on the electrochemical and spectroelectrochemical studies that gave insight into redox potentials of the four mitochondrial complexes and their homologues from bacterial respiratory chains using O2 as a terminal acceptor, thus providing crucial information about their reaction mechanism. Advantages and limitations of the use of the different techniques for the study of membrane proteins are presented. Electrocatalytic experiments are described that revealed specific features of the reaction with the substrates and inhibitors. An overview is given on the great variability of the redox and catalytic properties of the enzymes in different organisms that may be due to adaptation to the specific environments in which these enzymes function. The adaptation of the redox chain to the different types of quinone and substrates is analyzed, and future studies are discussed.</description><identifier>ISSN: 0009-2665</identifier><identifier>EISSN: 1520-6890</identifier><identifier>DOI: 10.1021/acs.chemrev.0c00249</identifier><identifier>PMID: 32820893</identifier><language>eng</language><publisher>United States: American Chemical Society</publisher><subject>Adaptation ; Chains ; Chemical Sciences ; Corrosion inhibitors ; Electrochemistry ; Enzymes ; Homology ; Membranes ; Other ; Proteins ; Quinones ; Reaction mechanisms ; Substrate inhibition ; Substrates</subject><ispartof>Chemical reviews, 2020-09, Vol.120 (18), p.10244-10297</ispartof><rights>Copyright American Chemical Society Sep 23, 2020</rights><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a473t-457d4329eb1504778e53963defae7cfe243968e2660e8028dff5e18cdd3f4aff3</citedby><cites>FETCH-LOGICAL-a473t-457d4329eb1504778e53963defae7cfe243968e2660e8028dff5e18cdd3f4aff3</cites><orcidid>0000-0001-6294-5163</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://pubs.acs.org/doi/pdf/10.1021/acs.chemrev.0c00249$$EPDF$$P50$$Gacs$$H</linktopdf><linktohtml>$$Uhttps://pubs.acs.org/doi/10.1021/acs.chemrev.0c00249$$EHTML$$P50$$Gacs$$H</linktohtml><link.rule.ids>230,314,780,784,885,2765,27076,27924,27925,56738,56788</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32820893$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://hal.science/hal-03341539$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Melin, Frederic</creatorcontrib><creatorcontrib>Hellwig, Petra</creatorcontrib><title>Redox Properties of the Membrane Proteins from the Respiratory Chain</title><title>Chemical reviews</title><addtitle>Chem. Rev</addtitle><description>This review focuses on the electrochemical and spectroelectrochemical studies that gave insight into redox potentials of the four mitochondrial complexes and their homologues from bacterial respiratory chains using O2 as a terminal acceptor, thus providing crucial information about their reaction mechanism. Advantages and limitations of the use of the different techniques for the study of membrane proteins are presented. Electrocatalytic experiments are described that revealed specific features of the reaction with the substrates and inhibitors. An overview is given on the great variability of the redox and catalytic properties of the enzymes in different organisms that may be due to adaptation to the specific environments in which these enzymes function. The adaptation of the redox chain to the different types of quinone and substrates is analyzed, and future studies are discussed.</description><subject>Adaptation</subject><subject>Chains</subject><subject>Chemical Sciences</subject><subject>Corrosion inhibitors</subject><subject>Electrochemistry</subject><subject>Enzymes</subject><subject>Homology</subject><subject>Membranes</subject><subject>Other</subject><subject>Proteins</subject><subject>Quinones</subject><subject>Reaction mechanisms</subject><subject>Substrate inhibition</subject><subject>Substrates</subject><issn>0009-2665</issn><issn>1520-6890</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNp9kctKAzEUhoMoWi9PIMiAG11MzXWSLKVeoaIUXYd05oRO6TQ1mRb79mZs7cKFq3ByvvOfy4_QOcF9gim5sWXslxNoAqz6uMSYcr2HekRQnBdK433UwxjrnBaFOELHMU5TKASVh-iIUUWx0qyH7kZQ-a_sLfgFhLaGmHmXtRPIXqAZBzuHLtVCPY-ZC775SY0gLupgWx_W2WBi6_kpOnB2FuFs-56gj4f798FTPnx9fB7cDnPLJWtzLmTFGdUwJgJzKRUIpgtWgbMgSweUp1BBGhiDwlRVzgkgqqwq5rh1jp2g643uxM7MItSNDWvjbW2eboem-8OMcZJEVySxVxt2EfznEmJrmjqWMJulnfwymtSsYFqkoyX08g869cswT5skikvNldQyUWxDlcHHGMDtJiDYdIaYZIjZGmK2hqSqi632ctxAtav5dSABNxugq971_U_yGy3Cl68</recordid><startdate>20200923</startdate><enddate>20200923</enddate><creator>Melin, Frederic</creator><creator>Hellwig, Petra</creator><general>American Chemical Society</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SR</scope><scope>8BQ</scope><scope>8FD</scope><scope>JG9</scope><scope>7X8</scope><scope>1XC</scope><orcidid>https://orcid.org/0000-0001-6294-5163</orcidid></search><sort><creationdate>20200923</creationdate><title>Redox Properties of the Membrane Proteins from the Respiratory Chain</title><author>Melin, Frederic ; Hellwig, Petra</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a473t-457d4329eb1504778e53963defae7cfe243968e2660e8028dff5e18cdd3f4aff3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Adaptation</topic><topic>Chains</topic><topic>Chemical Sciences</topic><topic>Corrosion inhibitors</topic><topic>Electrochemistry</topic><topic>Enzymes</topic><topic>Homology</topic><topic>Membranes</topic><topic>Other</topic><topic>Proteins</topic><topic>Quinones</topic><topic>Reaction mechanisms</topic><topic>Substrate inhibition</topic><topic>Substrates</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Melin, Frederic</creatorcontrib><creatorcontrib>Hellwig, Petra</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Engineered Materials Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><collection>MEDLINE - Academic</collection><collection>Hyper Article en Ligne (HAL)</collection><jtitle>Chemical reviews</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Melin, Frederic</au><au>Hellwig, Petra</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Redox Properties of the Membrane Proteins from the Respiratory Chain</atitle><jtitle>Chemical reviews</jtitle><addtitle>Chem. Rev</addtitle><date>2020-09-23</date><risdate>2020</risdate><volume>120</volume><issue>18</issue><spage>10244</spage><epage>10297</epage><pages>10244-10297</pages><issn>0009-2665</issn><eissn>1520-6890</eissn><abstract>This review focuses on the electrochemical and spectroelectrochemical studies that gave insight into redox potentials of the four mitochondrial complexes and their homologues from bacterial respiratory chains using O2 as a terminal acceptor, thus providing crucial information about their reaction mechanism. Advantages and limitations of the use of the different techniques for the study of membrane proteins are presented. Electrocatalytic experiments are described that revealed specific features of the reaction with the substrates and inhibitors. An overview is given on the great variability of the redox and catalytic properties of the enzymes in different organisms that may be due to adaptation to the specific environments in which these enzymes function. The adaptation of the redox chain to the different types of quinone and substrates is analyzed, and future studies are discussed.</abstract><cop>United States</cop><pub>American Chemical Society</pub><pmid>32820893</pmid><doi>10.1021/acs.chemrev.0c00249</doi><tpages>54</tpages><orcidid>https://orcid.org/0000-0001-6294-5163</orcidid></addata></record>
fulltext	fulltext
identifier	ISSN: 0009-2665
ispartof	Chemical reviews, 2020-09, Vol.120 (18), p.10244-10297
issn	0009-2665 1520-6890
language	eng
recordid	cdi_hal_primary_oai_HAL_hal_03341539v1
source	American Chemical Society Journals
subjects	Adaptation Chains Chemical Sciences Corrosion inhibitors Electrochemistry Enzymes Homology Membranes Other Proteins Quinones Reaction mechanisms Substrate inhibition Substrates
title	Redox Properties of the Membrane Proteins from the Respiratory Chain
url	https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-23T02%3A05%3A58IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_hal_p&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Redox%20Properties%20of%20the%20Membrane%20Proteins%20from%20the%20Respiratory%20Chain&rft.jtitle=Chemical%20reviews&rft.au=Melin,%20Frederic&rft.date=2020-09-23&rft.volume=120&rft.issue=18&rft.spage=10244&rft.epage=10297&rft.pages=10244-10297&rft.issn=0009-2665&rft.eissn=1520-6890&rft_id=info:doi/10.1021/acs.chemrev.0c00249&rft_dat=%3Cproquest_hal_p%3E2447948797%3C/proquest_hal_p%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2447948797&rft_id=info:pmid/32820893&rfr_iscdi=true