Switch maintenance chemotherapy versus observation after carboplatin and weekly paclitaxel doublet chemotherapy in elderly patients with advanced non–small cell lung cancer: IFCT-1201 MODEL trial

Maintenance chemotherapy is a reasonable choice for patients with metastatic non–small cell lung carcinoma (NSCLC) not progressing after induction therapy with a platinum-based doublet. Nevertheless, there have been no studies dedicated to elderly patients. We conducted a randomised trial in patient...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	European journal of cancer (1990) 2020-10, Vol.138, p.193-201
Hauptverfasser:	Quoix, Elisabeth, Audigier-Valette, Clarisse, Lavolé, Armelle, Molinier, Olivier, Westeel, Virginie, Barlesi, Fabrice, Le Treut, Jacques, Pichon, Eric, Dauba, Jérôme, Otto, Josiane, Moreau, Lionel, Madelaine, Jeannick, Dumont, Patrick, Margery, Jacques, Debieuvre, Didier, Renault, Patrick Aldo, Pujol, Jean-Louis, Langlais, Alexandra, Morin, Franck, Moro-Sibilot, Denis, Souquet, Pierre-Jean
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Aged Aged, 80 and over Antimetabolites, Antineoplastic Antimetabolites, Antineoplastic - administration & dosage Antimetabolites, Antineoplastic - adverse effects Antineoplastic Combined Chemotherapy Protocols Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Cancer Carboplatin Carboplatin - administration & dosage Carboplatin - adverse effects Carcinoma, Non-Small-Cell Lung Carcinoma, Non-Small-Cell Lung - drug therapy Carcinoma, Non-Small-Cell Lung - mortality Carcinoma, Non-Small-Cell Lung - secondary Chemotherapy Confidence intervals Creatinine Deoxycytidine Deoxycytidine - administration & dosage Deoxycytidine - adverse effects Deoxycytidine - analogs & derivatives Disease Progression Drug Administration Schedule Drug Substitution Elderly Epidermal growth factor receptors Female France Gemcitabine Humans Induction therapy Life Sciences Lung cancer Lung carcinoma Lung Neoplasms Lung Neoplasms - drug therapy Lung Neoplasms - mortality Lung Neoplasms - pathology Maintenance Maintenance Chemotherapy Male Metastases Mutation Neoplasm Staging Non-small cell lung carcinoma NSCLC Older people Paclitaxel Paclitaxel - administration & dosage Paclitaxel - adverse effects Pemetrexed Pemetrexed - administration & dosage Pemetrexed - adverse effects Platinum Progression-Free Survival Randomization Small cell lung carcinoma Squamous cell carcinoma Survival Time Factors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!