Positive End-Expiratory Pressure Setting in Adults With Acute Lung Injury and Acute Respiratory Distress Syndrome: A Randomized Controlled Trial

CONTEXT The need for lung protection is universally accepted, but the optimal level of positive end-expiratory pressure (PEEP) in patients with acute lung injury (ALI) or acute respiratory distress syndrome remains debated. OBJECTIVE To compare the effect on outcome of a strategy for setting PEEP ai...

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Veröffentlicht in:	JAMA : the journal of the American Medical Association 2008-02, Vol.299 (6), p.646-655
Hauptverfasser:	Mercat, Alain, Richard, Jean-Christophe M, Vielle, Bruno, Jaber, Samir, Osman, David, Diehl, Jean-Luc, Lefrant, Jean-Yves, Prat, Gwenaël, Richecoeur, Jack, Nieszkowska, Ania, Gervais, Claude, Baudot, Jérôme, Bouadma, Lila, Brochard, Laurent, Expiratory Pressure (Express) Study Group, for the
Format:	Artikel
Sprache:	eng
Schlagworte:	Adults Aged Airway management Biological and medical sciences Clinical outcomes Clinical trials Female General aspects Hospital Mortality Humans Life Sciences Male Medical sciences Middle Aged Pneumology Positive-Pressure Respiration Respiratory diseases Respiratory Distress Syndrome, Adult - physiopathology Respiratory Distress Syndrome, Adult - therapy Respiratory system : syndromes and miscellaneous diseases Survival Analysis Tidal Volume Ventilator Weaning Ventilators
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