Vitamin D3–elicited CD14+ human skin dendritic cells promote thymic stromal lymphopoietin–independent type 2 T‐helper responses

Background Immune modulation by vitamin D3 through dendritic cells (DCs) remains controversial. Human DCs exposed in vitro counteract type‐1 T‐helper (Th1) differentiation and induce regulatory T cells. However, cutaneous application on mice promotes Th2‐driven inflammation resembling atopic dermati...

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Veröffentlicht in:	Allergy (Copenhagen) 2021-07, Vol.76 (7), p.2044-2056
Hauptverfasser:	Brulefert, Adrien, Hoste, Astrid, Muller, Quentin, Fauny, Jean‐Daniel, Mueller, Christopher G., Flacher, Vincent
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergies Atopic dermatitis CD14 antigen CD4 antigen Cell differentiation Cell proliferation dendritic cell Dendritic cells Dermatitis Eczema Explants Helper cells Immunology Immunomodulation Immunoregulation Keratinocytes Life Sciences Lymphocytes T Phenotypes Skin T helper 2 Thymic stromal lymphopoietin Thymus Vitamin D3
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