Expression of neurotensin receptor 1 in endometrial adenocarcinoma is correlated with histological grade and clinical outcome

The promalignant effects of neurotensin (NTS) are sustained in many solid tumors, including hormone-dependent cancers. As the endometrium is also subjected to hormonal regulation, we evaluated the contribution of NTS to endometrial carcinogenesis. Neurotensin receptor 1 (NTSR1) expression and NTSR1...

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Veröffentlicht in:	Virchows Archiv : an international journal of pathology 2017-10, Vol.471 (4), p.521-530
Hauptverfasser:	Agopiantz, Mikaël, Forgez, Patricia, Casse, Jean-Matthieu, Lacomme, Stéphanie, Charra-Brunaud, Claire, Clerc-Urmès, Isabelle, Morel, Olivier, Bonnet, Céline, Guéant, Jean-Louis, Vignaud, Jean-Michel, Gompel, Anne, Gauchotte, Guillaume
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Adenocarcinoma - mortality Adenocarcinoma - pathology Adult Aged Benign Bioengineering Biomarkers, Tumor - analysis Cancer Carcinogenesis Carcinogens Carcinoma Clinical outcomes Computer Science Correlation Disease-Free Survival DNA methylation Endometrial cancer Endometrial Neoplasms - mortality Endometrial Neoplasms - pathology Endometrium Female Genomes Human health and pathology Humans Immunohistochemistry Kaplan-Meier Estimate Life Sciences Medical Imaging Medicine Medicine & Public Health Methylation Middle Aged mRNA Multivariate analysis Neurotensin Nuclear medicine Original Article Pathology Prognosis Proportional Hazards Models Quality Receptors, Neurotensin - analysis Receptors, Neurotensin - biosynthesis Ribonucleic acid RNA Solid tumors Solitary tract nucleus Survival Treatment Outcome Tumors Uterine cancer
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