Design and synthesis of zinc protoporphyrin IX-adamantane/cyclodextrin/cellulose nanocrystals complexes for anticancer photodynamic therapy

[Display omitted] Two protoporphyrin IX (PpIX) adamantane derivatives were synthesized and then metallated with zinc. The Zn-PpIX derivatives, exhibiting a high singlet oxygen quantum yield, were tested for their photodynamic activity against the HT-29 cell line. In order to enhance their water-solu...

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Veröffentlicht in:	Bioorganic & medicinal chemistry letters 2021-06, Vol.41, p.128024-128024, Article 128024
Hauptverfasser:	Ndong Ntoutoume, Gautier M.A., Granet, Robert, Mbakidi, Jean-Pierre, Constantin, Eléna, Bretin, Ludovic, Léger, David Y., Liagre, Bertrand, Chaleix, Vincent, Brégier, Frédérique, Sol, Vincent
Format:	Artikel
Sprache:	eng
Schlagworte:	Cellulose nanocrystals Chemical Sciences Colorectal cancer Nanoparticles Organic chemistry Photodynamic therapy Porphyrins
Online-Zugang:	Volltext
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