Physical activity and adipokine levels in individuals with type 2 diabetes: A literature review and practical applications
We review the effects of acute and long-term physical activity on adipokine levels in individuals with type 2 diabetes (T2D). Three electronic databases were searched. Studies made in animal models were excluded, while studies based on participants with and without T2D, and also studies with type 1...
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| Veröffentlicht in: | Reviews in endocrine & metabolic disorders 2021-12, Vol.22 (4), p.987-1011 |
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| creator | Zouhal, Hassane Zare-kookandeh, Navabeh Haghighi, Marjan Mosalman Daraei, Ali de Sousa, Maysa Soltani, Mohammad Abderrahman, Abderraouf Ben M. Tijani, Jed Hackney, Anthony C. Laher, Ismail Saeidi, Ayoub |
| description | We review the effects of acute and long-term physical activity on adipokine levels in individuals with type 2 diabetes (T2D). Three electronic databases were searched. Studies made in animal models were excluded, while studies based on participants with and without T2D, and also studies with type 1 diabetes were included. Of the 2,450 citations, 63 trials, including randomised control trials, cross-sectional and longitudinal studies, met our inclusion criteria. Seventy and five percent of studies reported the effects of physical activity on tumor necrosis factor-alpha (TNFα), interleukin 6 (IL-6), adiponectin, visfatin, omentin-1, and leptin levels. There are no robust results due to variations in exercise modality, intensity, duration, and also differences in cohort characteristics in the literature. Only four studies described the effects of an acute session of physical activity on adipokine levels. Overall, physical activity improves diabetes status by regulating adipokine levels. However, long-term aerobic + resistance training combined with dietary modifications is likely to be a more effective strategy for improving adipokines profiles in patients with type 2 diabetes. |
| doi_str_mv | 10.1007/s11154-021-09657-x |
| format | Article |
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Tijani, Jed ; Hackney, Anthony C. ; Laher, Ismail ; Saeidi, Ayoub</creator><creatorcontrib>Zouhal, Hassane ; Zare-kookandeh, Navabeh ; Haghighi, Marjan Mosalman ; Daraei, Ali ; de Sousa, Maysa ; Soltani, Mohammad ; Abderrahman, Abderraouf Ben ; M. Tijani, Jed ; Hackney, Anthony C. ; Laher, Ismail ; Saeidi, Ayoub</creatorcontrib><description>We review the effects of acute and long-term physical activity on adipokine levels in individuals with type 2 diabetes (T2D). Three electronic databases were searched. Studies made in animal models were excluded, while studies based on participants with and without T2D, and also studies with type 1 diabetes were included. Of the 2,450 citations, 63 trials, including randomised control trials, cross-sectional and longitudinal studies, met our inclusion criteria. Seventy and five percent of studies reported the effects of physical activity on tumor necrosis factor-alpha (TNFα), interleukin 6 (IL-6), adiponectin, visfatin, omentin-1, and leptin levels. There are no robust results due to variations in exercise modality, intensity, duration, and also differences in cohort characteristics in the literature. Only four studies described the effects of an acute session of physical activity on adipokine levels. Overall, physical activity improves diabetes status by regulating adipokine levels. 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Tijani, Jed</creatorcontrib><creatorcontrib>Hackney, Anthony C.</creatorcontrib><creatorcontrib>Laher, Ismail</creatorcontrib><creatorcontrib>Saeidi, Ayoub</creatorcontrib><title>Physical activity and adipokine levels in individuals with type 2 diabetes: A literature review and practical applications</title><title>Reviews in endocrine & metabolic disorders</title><addtitle>Rev Endocr Metab Disord</addtitle><addtitle>Rev Endocr Metab Disord</addtitle><description>We review the effects of acute and long-term physical activity on adipokine levels in individuals with type 2 diabetes (T2D). Three electronic databases were searched. Studies made in animal models were excluded, while studies based on participants with and without T2D, and also studies with type 1 diabetes were included. Of the 2,450 citations, 63 trials, including randomised control trials, cross-sectional and longitudinal studies, met our inclusion criteria. Seventy and five percent of studies reported the effects of physical activity on tumor necrosis factor-alpha (TNFα), interleukin 6 (IL-6), adiponectin, visfatin, omentin-1, and leptin levels. There are no robust results due to variations in exercise modality, intensity, duration, and also differences in cohort characteristics in the literature. Only four studies described the effects of an acute session of physical activity on adipokine levels. Overall, physical activity improves diabetes status by regulating adipokine levels. However, long-term aerobic + resistance training combined with dietary modifications is likely to be a more effective strategy for improving adipokines profiles in patients with type 2 diabetes.</description><subject>Adipokines</subject><subject>Adiponectin</subject><subject>Animal models</subject><subject>Clinical trials</subject><subject>Cross-Sectional Studies</subject><subject>Diabetes</subject><subject>Diabetes mellitus (insulin dependent)</subject><subject>Diabetes mellitus (non-insulin dependent)</subject><subject>Diabetes Mellitus, Type 2</subject><subject>Endocrinology</subject><subject>Exercise</subject><subject>Exercise - physiology</subject><subject>Humans</subject><subject>Interleukin 6</subject><subject>Internal Medicine</subject><subject>Leptin</subject><subject>Life Sciences</subject><subject>Literature reviews</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Physical activity</subject><subject>Physical training</subject><subject>Tumor necrosis factor-α</subject><issn>1389-9155</issn><issn>1573-2606</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp9kcFu1DAQhi0EomXhBTggS1zgEBjbsRNzW1VAK60EBzhbTjxhXbJJsJ1tl6fHuymtxAHJkmfsb_6x5yfkJYN3DKB6HxljsiyAswK0klVx-4icM1mJgitQj3Msal1oJuUZeRbjNWRSafmUnAmhBatBnJPfX7eH6FvbU9smv_fpQO3gqHV-Gn_6AWmPe-wj9UNeLgNutjm98WlL02FCyqnztsGE8QNd094nDDbNAWnAvcebk9oUjuKnJtPU5yD5cYjPyZMua-GLu31Fvn_6-O3isth8-Xx1sd4UbQk6FQxsJUF1IEXrAMvStbruVFs66XhlLetKzZxGhl0jQWpd21o1rCkV7ypRgViRt4vu1vZmCn5nw8GM1pvL9cYcz0BwLvPc9iyzbxZ2CuOvGWMyOx9b7Hs74DhHwyWHWqrj_Fbk9T_o9TiHIf_EcMWkBq15nSm-UG0YYwzY3b-AgTm6aBYXTfbGnFw0t7no1Z303OzQ3Zf8tS0DYgFivhp-YHjo_R_ZP1R6qFs</recordid><startdate>20211201</startdate><enddate>20211201</enddate><creator>Zouhal, Hassane</creator><creator>Zare-kookandeh, Navabeh</creator><creator>Haghighi, Marjan Mosalman</creator><creator>Daraei, Ali</creator><creator>de Sousa, Maysa</creator><creator>Soltani, Mohammad</creator><creator>Abderrahman, Abderraouf Ben</creator><creator>M. 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| ispartof | Reviews in endocrine & metabolic disorders, 2021-12, Vol.22 (4), p.987-1011 |
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| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Adipokines Adiponectin Animal models Clinical trials Cross-Sectional Studies Diabetes Diabetes mellitus (insulin dependent) Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 Endocrinology Exercise Exercise - physiology Humans Interleukin 6 Internal Medicine Leptin Life Sciences Literature reviews Medicine Medicine & Public Health Physical activity Physical training Tumor necrosis factor-α |
| title | Physical activity and adipokine levels in individuals with type 2 diabetes: A literature review and practical applications |
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