Major involvement of cathepsin B in the intracellular proteolytic processing of exogenous IgGs in U937 cells

Monoclonal antibodies used for diagnostic and therapeutic purposes behave as antigens when injected into patients. They are recognized by T cells in a processed form and in a major histocompatibility complex class II restricted fashion. Monoclonal murine IgG2a were used as a model to analyse the ear...

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Veröffentlicht in:Molecular immunology 1993-08, Vol.30 (11), p.1033-1039
Hauptverfasser: santoro, Lyse, Reboul, Angeline, Journet, Agnès M., Colomb, Maurice G.
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Sprache:eng
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