Hepatitis E virus replication in human intestinal cells

ObjectiveHepatitis E virus (HEV), one of the most common agent of acute hepatitis worldwide, is mainly transmitted enterically, via contaminated water for HEV genotypes 1 (HEV1) and HEV2, or by eating raw or undercooked infected meat for HEV genotype 3 (HEV3) and HEV4. However, little is known about...

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Veröffentlicht in:	Gut 2020-05, Vol.69 (5), p.901-910
Hauptverfasser:	Marion, Olivier, Lhomme, Sebastien, Nayrac, Manon, Dubois, Martine, Pucelle, Mélanie, Requena, Mary, Migueres, Marion, Abravanel, Florence, Peron, Jean Marie, Carrere, Nicolas, Suc, Bertrand, Delobel, Pierre, Kamar, Nassim, Izopet, Jacques
Format:	Artikel
Sprache:	eng
Schlagworte:	antiviral chemotherapy Cells, Cultured Centrifugation enteric infections Enterocytes Epithelial Cells Explants Genomes Genotype Genotype & phenotype Genotypes Hepatitis hepatitis E Hepatitis E virus / genetics Hepatocytes / drug effects Hepatocytes / virology Hepatology Human health and pathology Humans Infections Infectious diseases Intestine, Small / cytology Life Sciences Lipids Liver Meat Patients Proteins Ribavirin Ribavirin / pharmacology Ribonucleic acid RNA RNA polymerase RNA, Viral / genetics Sensitivity and Specificity Small intestine Surgery Transplants & implants Virions Virus Replication / genetics Viruses
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