Essential role for Bclaf1 in lung development and immune system function

Bcl-2 associated factor 1 (Bclaf1) is a nuclear protein that was originally identified in a screen of proteins that interact with the adenoviral bcl-2 homolog E1B19K. Overexpression of Bclaf1 was shown to result in apoptosis and transcriptional repression that was reversible in the presence of Bcl-2...

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Veröffentlicht in:	Cell death and differentiation 2009-02, Vol.16 (2), p.331-339
Hauptverfasser:	McPherson, J Peter, Sarras, H, Lemmers, B, Tamblyn, L, Migon, E, Matysiak-Zablocki, E, Hakem, A, Azami, S Alizadeh, Cardoso, R, Fish, J, Sanchez, O, Post, M, Hakem, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal biology Animals Apoptosis bcl-2-Associated X Protein - metabolism Biochemistry Biochemistry, Molecular Biology Biomedical and Life Sciences Biophysics Cancer Cell Biology Cell Cycle Analysis Cell death Cellular Biology Cloning DNA-Binding Proteins - genetics DNA-Binding Proteins - physiology Homeostasis Homozygote Immune system Immunology Life Sciences Localization Lung - growth & development Lymphocytes - immunology Membrane Proteins - metabolism Mice Mice, Knockout Muscular dystrophy Nuclear Proteins - metabolism original-paper Proteins Repressor Proteins - genetics Repressor Proteins - physiology Smooth muscle Stem Cells
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