Protein homodimer sequestration with small molecules: Focus on PD-L1

[Display omitted] Monoclonal antibodies targeting the PD-1/PD-L1 immune checkpoint have emerged as efficient cancer biotherapeutics. In parallel, small molecules targeting PD-L1 are actively searched to offer novel therapeutic opportunities and to reduce treatment costs. Thus far, all PD-L1 small mo...

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Veröffentlicht in:	Biochemical pharmacology 2020-04, Vol.174, p.113821-113821, Article 113821
Hauptverfasser:	Bailly, Christian, Vergoten, Gérard
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Chemical Sciences Immunotherapy Life Sciences Max or physical chemistry PD-L1 Protein dimer Theoretical and
Online-Zugang:	Volltext
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