Surface Co-presentation of BMP-2 and integrin selective ligands at the nanoscale favors α5β1 integrin-mediated adhesion

Here we present the use of surface nanopatterning of covalently immobilized BMP-2 and integrin selective ligands to determine the specificity of their interactions in regulating cell adhesion and focal adhesion assembly. Gold nanoparticle arrays carrying single BMP-2 dimers are prepared by block-cop...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Biomaterials 2021-01, Vol.267, p.120484-120484, Article 120484
Hauptverfasser:	Posa, Francesca, Baha-Schwab, Elisabeth H., Wei, Qiang, Di Benedetto, Adriana, Neubauer, Stefanie, Reichart, Florian, Kessler, Horst, Spatz, Joachim P., Albiges-Rizo, Corinne, Mori, Giorgio, Cavalcanti-Adam, Elisabetta Ada
Format:	Artikel
Sprache:	eng
Schlagworte:	BMP-2 Click chemistry Focal adhesions Integrins Life Sciences Surface functionalization
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!