Contribution of Raman spectroscopy in nephrology: a candidate technique to detect hydroxyethyl starch of third generation in osmotic renal lesions

Contribution of Raman spectroscopy in nephrology: a candidate technique to detect hydroxyethyl starch of third generation in osmotic renal lesions

HydroxyEthyl Starch (HES) has been one of the most commonly used colloid volume expanders in intensive care units for over 50 years. The first and second generation HES, with a high molecular weight (≥200 kD) and a high degree of substitution (≥0.5), has been associated with both renal dysfunction a...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Analyst (London) 2015-01, Vol.140 (21), p.7382-7390
Hauptverfasser: Vuiblet, V, Nguyen, T T, Wynckel, A, Fere, M, Van-Gulick, L, Untereiner, V, Birembaut, P, Rieu, P, Piot, O
Format: Artikel
Sprache:eng
Schlagworte:
Acute Kidney Injury
Adult
Aged
Biopsy
Colloids - chemistry
Female
Humans
Hydroxyethyl Starch Derivatives - analysis
Hydroxyethyl Starch Derivatives - chemistry
Kidney - pathology
Kidney Diseases - metabolism
Kidney Diseases - pathology
Kidney Transplantation
Kidneys
Lesions
Life Sciences
Male
Middle Aged
Monocytes - cytology
Nephrology - methods
Osmosis
Patients
Pixels
Raman spectroscopy
Renal function
Spectrum Analysis, Raman - methods
Starches
Vibration
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:HydroxyEthyl Starch (HES) has been one of the most commonly used colloid volume expanders in intensive care units for over 50 years. The first and second generation HES, with a high molecular weight (≥200 kD) and a high degree of substitution (≥0.5), has been associated with both renal dysfunction and osmotic nephrosis-like lesions in histological studies. Recently, third generation HES (130 kD/
ISSN:0003-2654
1364-5528
DOI:10.1039/c5an00821b