Enhanced anticancer activity of nanopreparation containing an MMP2-sensitive PEG-drug conjugate and cell-penetrating moiety

In response to the challenges of cancer chemotherapeutics, including poor physicochemical properties, low tumor targeting, insufficient tumor cell internalization/bioavailability, and side effects, we developed a unique tumor-targeted micellar drug-delivery platform. Using paclitaxel as a model ther...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2013-09, Vol.110 (42), p.17047-17052
Hauptverfasser:	Zhu, Lin, Perche, Federico, Wang, Tao, Taigind, Anton, Torchilin, Vladimir P, Fenway, The
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemical Sciences Medicinal Chemistry
Online-Zugang:	Volltext
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