Matrix metalloproteinase 2-sensitive multifunctional polymeric micelles for tumor-specific co-delivery of siRNA and hydrophobic drugs

Stimulus-sensitive Matrix metalloproteinase siRNA and drug delivery Tumor targeting a b s t r a c t Co-delivery of hydrophilic siRNA and hydrophobic drugs is one of the major challenges for nanomaterial-based medicine. Here, we present a simple but multifunctional micellar platform constructed by a...

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Veröffentlicht in:	Biomaterials 2014-04, Vol.35 (13), p.4213-4222
Hauptverfasser:	Wang, Tao, Zhu, Lin, Perche, Federico, Taigind, Anton, Torchilin, Vladimir P
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemical Sciences Medicinal Chemistry
Online-Zugang:	Volltext
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