DNA double-strand break repair signalling: The case of RAD51 post-translational regulation

DNA double-strand breaks (DSBs) are the major lethal lesion induced by ionizing radiation or by replication block. However, cells can take advantage of DSB-induced recombination in order to generate genetic diversity in physiological processes such as meiosis and V(D)J recombination. Two main altern...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cellular Signalling 2002-12, Vol.14 (12), p.969-975
Hauptverfasser:	Daboussi, Fayza, Dumay, Anne, Delacôte, Fabien, Lopez, Bernard S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Ataxia Telangiectasia Mutated Proteins BCL-2 BCR/ABL Cell Cycle Proteins DNA Damage DNA Repair DNA-Binding Proteins - metabolism Double-strand break repair Fusion Proteins, bcr-abl - metabolism Genetic Predisposition to Disease Homologous recombination Life Sciences Models, Genetic Neoplasms - genetics Non-homologous end-joining Protein Processing, Post-Translational Protein-Serine-Threonine Kinases - metabolism Proto-Oncogene Proteins c-bcl-2 - metabolism RAD51 Rad51 Recombinase Recombination, Genetic Signal Transduction Tumor Suppressor Proteins
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!