Extracellular vesicles released by polycyclic aromatic hydrocarbons-treated hepatocytes trigger oxidative stress in recipient hepatocytes by delivering iron

A growing body of evidences indicate the major role of extracellular vesicles (EVs) as players of cell communication in the pathogenesis of liver diseases. EVs are membrane-enclosed vesicles released by cells into the extracellular environment. Oxidative stress is also a key component of liver disea...

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Veröffentlicht in:	Free radical biology & medicine 2020-11, Vol.160, p.246-262
Hauptverfasser:	van Meteren, Nettie, Lagadic-Gossmann, Dominique, Podechard, Normand, Gobart, Dimitri, Gallais, Isabelle, Chevanne, Martine, Collin, Aurore, Burel, Agnès, Dupont, Aurélien, Rault, Ludivine, Chevance, Soizic, Gauffre, Fabienne, Le Ferrec, Eric, Sergent, Odile
Format:	Artikel
Sprache:	eng
Schlagworte:	Extracellular vesicles Ferritin Hepatocytes Life Sciences Lipid peroxidation LMW iron Lysosomes Mitochondria NADPH oxidase Polycyclic aromatic hydrocarbons
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