Long-term development of human iPSC-derived pyramidal neurons quantified after transplantation into the neonatal mouse cortex

One of the main obstacles for studying the molecular and cellular mechanisms underlying human neurodevelopment in vivo is the scarcity of experimental models. The discovery that neurons can be generated from human induced pluripotent stem cells (hiPSCs) paves the way for novel approaches that are st...

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Veröffentlicht in:Developmental biology 2020-05, Vol.461 (1), p.86-95
Hauptverfasser: D’Alessio, Rosa, Koukouli, Fani, Blanchard, Stéphane, Catteau, Julie, Raïs, Célia, Lemonnier, Thomas, Féraud, Olivier, Bennaceur-Griscelli, Annelise, Groszer, Matthias, Maskos, Uwe
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Sprache:eng
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