BRAF mutation is not associated with an increased risk of recurrence in patients undergoing resection of colorectal liver metastases

Background BRAF mutation is associated with a poor prognosis in patients with metastatic colorectal cancer. For patients with resectable colorectal liver metastases (CRLMs), the prognostic impact of BRAF mutation is unknown and the benefit of surgery debated. This nationwide intergroup (ACHBT, FRENC...

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Veröffentlicht in:	British journal of surgery 2019-08, Vol.106 (9), p.1237-1247
Hauptverfasser:	Bachet, J.‐B., Moreno‐Lopez, N., Vigano, L., Marchese, U., Gelli, M., Raoux, L., Truant, S., Laurent, C., Herrero, A., Le Roy, B., Deguelte Lardiere, S., Passot, G., Hautefeuille, V., De La Fouchardiere, C., Artru, P., Ameto, T., Mabrut, J. Y., Schwarz, L., Rousseau, B., Lepère, C., Coriat, R., Brouquet, A., Sa Cunha, A., Benoist, S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Case-Control Studies Colorectal cancer Colorectal Neoplasms - genetics Colorectal Neoplasms - mortality Colorectal Neoplasms - pathology Colorectal Neoplasms - surgery Disease-Free Survival Female Hepatectomy Human health and pathology Humans Life Sciences Liver Neoplasms - genetics Liver Neoplasms - mortality Liver Neoplasms - secondary Liver Neoplasms - surgery Male Medical prognosis Metastasis Middle Aged Mutation Mutation - genetics Neoplasm Recurrence, Local - genetics Proto-Oncogene Proteins B-raf - genetics Surgery Survival Analysis
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