Antisense oligonucleotide targeting the transforming growth factor beta 1 increases expression of specific genes and functions of Leydig cells

Transforming growth factor beta 1 (TGF beta 1) has been reported to be a potent inhibitor of differentiated functions of many steroidogenic cells. Porcine Leyding cells (LC), as well as Sertoli cells (SC), express TGF beta 1 mRNA and secrete this peptide, suggesting that it might play an autocrine r...

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Veröffentlicht in:	European Journal of Biochemistry 1998-10, Vol.257 (2), p.506-514
Hauptverfasser:	Roy, CL, Leduque, P, Li, J Y, Saez, J M, Langlois, D
Format:	Artikel
Sprache:	eng
Schlagworte:	Life Sciences oligonucleotides transforming growth factor-^b
Online-Zugang:	Volltext
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