Pregnancy-associated plasma protein-A (PAPP-A) in ovine, bovine, porcine, and equine ovarian follicles: involvement in IGF binding protein-4 proteolytic degradation and mRNA expression during follicular development

IGF binding protein-4 (IGFBP-4) proteolytic degradation is a common feature of preovulatory follicles from human, ovine, bovine, porcine, and equine ovary. In all these species, the protease is a zinc-dependent metalloprotease and its ability to degrade IGFBP-4 is IGF dependent. The human intrafolli...

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Veröffentlicht in:	Endocrinology (Philadelphia) 2001-12, Vol.142 (12), p.5243-5253
Hauptverfasser:	Mazerbourg, S, Overgaard, M T, Oxvig, C, Christiansen, M, Conover, C A, Laurendeau, I, Vidaud, M, Tosser-Klopp, G, Zapf, J, Monget, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence - genetics Animals Aromatase - genetics Base Sequence - genetics Cattle Chromosome Mapping Computer Science DNA, Complementary - genetics Female Follicular Fluid - metabolism Follicular Phase - physiology Granulosa Cells - metabolism Horses Humans Insulin-Like Growth Factor Binding Protein 4 - metabolism Life Sciences Molecular Sequence Data Ovarian Follicle - physiology Peptide Hydrolases - metabolism Pregnancy-Associated Plasma Protein-A - genetics Pregnancy-Associated Plasma Protein-A - physiology Receptors, LH - genetics Recombinant Proteins RNA, Messenger - metabolism Sheep Swine
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