Cellular Adhesion of Primary Sertoli Cells Affects Responsiveness of the Extracellular Signal-Regulated Kinases 1 and 2 to Follicle-Stimulating Hormone but Not to Epidermal Growth Factor

The cellular adhesion status and the exposure to soluble growth factors both contribute to mitogen-activated protein (MAP) kinase activation. To date, however, whether mitogens acting through G-protein-coupled receptors (GPCRs) need cell adhesion to activate MAP kinases/extracellular signal-regulate...

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Veröffentlicht in:	Archives of biochemistry and biophysics 2002-03, Vol.399 (2), p.245-250
Hauptverfasser:	Crépieux, P., Martinat, N., Marion, S., Guillou, F., Reiter, E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals cAMP cell adhesion Cell Adhesion - physiology Computer Science EGF-R Enzyme Activation Epidermal Growth Factor - metabolism ERK MAP kinases Follicle Stimulating Hormone - metabolism FSH-R Life Sciences Male Mitogen-Activated Protein Kinase 1 - metabolism Mitogen-Activated Protein Kinase 3 Mitogen-Activated Protein Kinases - metabolism Phosphorylation Rats Rats, Wistar Receptor Protein-Tyrosine Kinases - metabolism Receptor, Epidermal Growth Factor - metabolism Receptors, FSH - metabolism Sertoli cell Sertoli Cells - physiology Signal Transduction - physiology
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