Tumor necrosis factorα and insulin-like growth factor-I in the brain: Is the whole greater than the sum of its parts?

The cytokine tumor necrosis factorα (TNFα) and the hormone insulin-like growth factor-I (IGF-I) have both been shown to regulate inflammatory events in the central nervous system (CNS). This review summarizes the seemingly independent roles of TNFα and IGF-I in promoting and inhibiting neurodegenera...

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Veröffentlicht in:Journal of Neuroimmunology 2001-10, Vol.119 (2), p.151-165
Hauptverfasser: Venters, Homer D., Broussard, Suzanne R., Zhou, Jian-Hua, Bluthé, Rose-Marie, Freund, Gregory G., Johnson, Rodney W., Dantzer, Robert, Kelley, Keith W.
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Sprache:eng
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