Metabolism of trans and conjugated fatty acids
Trans fatty acids (FA) enter all the metabolic pathways of bioconversion, oxidation and lipid storage and are incorporated into all tissues. They also interfere with the polyunsaturated FA metabolic pathways. Among trans FA, major attention is paid to elaidic and vaccenic acids. The latter is biocon...
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Veröffentlicht in: | European journal of lipid science and technology 2007-09, Vol.109 (9), p.930-934 |
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container_title | European journal of lipid science and technology |
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creator | Chardigny, Jean-Michel Clouet, Pierre Combe, Nicole Quignard-Boulangé, Annie Schmitt, Bernard Lagarde, Michel Léger, Claude-Louis |
description | Trans fatty acids (FA) enter all the metabolic pathways of bioconversion, oxidation and lipid storage and are incorporated into all tissues. They also interfere with the polyunsaturated FA metabolic pathways. Among trans FA, major attention is paid to elaidic and vaccenic acids. The latter is bioconverted into rumenic acid, a conjugated linoleic acid (CLA) isomer, through the Δ9 desaturase pathway. Considering CLA isomers, they are also bioconverted by desaturases and the elongation pathway, but the significance of this conversion is not fully understood. This review considers these different aspects, with particular attention to human data. |
doi_str_mv | 10.1002/ejlt.200600279 |
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They also interfere with the polyunsaturated FA metabolic pathways. Among trans FA, major attention is paid to elaidic and vaccenic acids. The latter is bioconverted into rumenic acid, a conjugated linoleic acid (CLA) isomer, through the Δ9 desaturase pathway. Considering CLA isomers, they are also bioconverted by desaturases and the elongation pathway, but the significance of this conversion is not fully understood. This review considers these different aspects, with particular attention to human data.</description><identifier>ISSN: 1438-7697</identifier><identifier>EISSN: 1438-9312</identifier><identifier>DOI: 10.1002/ejlt.200600279</identifier><language>eng</language><publisher>Weinheim: Wiley-VCH Verlag</publisher><subject>Biochemistry ; Biochemistry, Molecular Biology ; conjugated linoleic acids ; Life Sciences ; metabolism ; Trans fatty acids</subject><ispartof>European journal of lipid science and technology, 2007-09, Vol.109 (9), p.930-934</ispartof><rights>Copyright © 2007 WILEY‐VCH Verlag GmbH & Co. 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J. Lipid Sci. Technol</addtitle><description>Trans fatty acids (FA) enter all the metabolic pathways of bioconversion, oxidation and lipid storage and are incorporated into all tissues. They also interfere with the polyunsaturated FA metabolic pathways. Among trans FA, major attention is paid to elaidic and vaccenic acids. The latter is bioconverted into rumenic acid, a conjugated linoleic acid (CLA) isomer, through the Δ9 desaturase pathway. Considering CLA isomers, they are also bioconverted by desaturases and the elongation pathway, but the significance of this conversion is not fully understood. This review considers these different aspects, with particular attention to human data.</description><subject>Biochemistry</subject><subject>Biochemistry, Molecular Biology</subject><subject>conjugated linoleic acids</subject><subject>Life Sciences</subject><subject>metabolism</subject><subject>Trans fatty acids</subject><issn>1438-7697</issn><issn>1438-9312</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><recordid>eNqFkD1PwzAQhi0EEqWwspKVIeEcx3Y8VoW2oAADrRgtf5aUtEFx-Oi_J1Wqio3p7l49zw0vQpcYEgyQ3rhV1SYpAOsOLo7QAGckjwXB6fF-50zwU3QWwgoABGMwQMmja5WuqzKso9pHbaM2IVIbG5l6s_pcqtbZyKu23UbKlDacoxOvquAu9nOIFpO7-XgWF8_T-_GoiE1GsYitFsSmxlmdZYJrLTJuKMkyDcRzZiylmhImQGultaaGYPDGckUxVSbFngzRdf_3TVXyoynXqtnKWpVyNirkLoOUMZZj8YU7NulZ09QhNM4fBAxy14zcNSMPzXSC6IXvsnLbf2h591DM_7px75ahdT8HVzXvknHCqXx9msrbnMOciYmcdPxVz3tVS7VsyiAXLylgApBjDESQX3tTfwA</recordid><startdate>20070901</startdate><enddate>20070901</enddate><creator>Chardigny, Jean-Michel</creator><creator>Clouet, Pierre</creator><creator>Combe, Nicole</creator><creator>Quignard-Boulangé, Annie</creator><creator>Schmitt, Bernard</creator><creator>Lagarde, Michel</creator><creator>Léger, Claude-Louis</creator><general>Wiley-VCH Verlag</general><general>WILEY-VCH Verlag</general><general>WILEY‐VCH Verlag</general><general>Wiley-VCH Verlag [2000-....]</general><scope>FBQ</scope><scope>BSCLL</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>1XC</scope></search><sort><creationdate>20070901</creationdate><title>Metabolism of trans and conjugated fatty acids</title><author>Chardigny, Jean-Michel ; Clouet, Pierre ; Combe, Nicole ; Quignard-Boulangé, Annie ; Schmitt, Bernard ; Lagarde, Michel ; Léger, Claude-Louis</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4519-db93d2cedb4497bb947c5344b03f76cd55b53690bbabbb5c310fcd7a515ac21f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Biochemistry</topic><topic>Biochemistry, Molecular Biology</topic><topic>conjugated linoleic acids</topic><topic>Life Sciences</topic><topic>metabolism</topic><topic>Trans fatty acids</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chardigny, Jean-Michel</creatorcontrib><creatorcontrib>Clouet, Pierre</creatorcontrib><creatorcontrib>Combe, Nicole</creatorcontrib><creatorcontrib>Quignard-Boulangé, Annie</creatorcontrib><creatorcontrib>Schmitt, Bernard</creatorcontrib><creatorcontrib>Lagarde, Michel</creatorcontrib><creatorcontrib>Léger, Claude-Louis</creatorcontrib><collection>AGRIS</collection><collection>Istex</collection><collection>CrossRef</collection><collection>Hyper Article en Ligne (HAL)</collection><jtitle>European journal of lipid science and technology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chardigny, Jean-Michel</au><au>Clouet, Pierre</au><au>Combe, Nicole</au><au>Quignard-Boulangé, Annie</au><au>Schmitt, Bernard</au><au>Lagarde, Michel</au><au>Léger, Claude-Louis</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Metabolism of trans and conjugated fatty acids</atitle><jtitle>European journal of lipid science and technology</jtitle><addtitle>Eur. J. Lipid Sci. Technol</addtitle><date>2007-09-01</date><risdate>2007</risdate><volume>109</volume><issue>9</issue><spage>930</spage><epage>934</epage><pages>930-934</pages><issn>1438-7697</issn><eissn>1438-9312</eissn><abstract>Trans fatty acids (FA) enter all the metabolic pathways of bioconversion, oxidation and lipid storage and are incorporated into all tissues. They also interfere with the polyunsaturated FA metabolic pathways. Among trans FA, major attention is paid to elaidic and vaccenic acids. The latter is bioconverted into rumenic acid, a conjugated linoleic acid (CLA) isomer, through the Δ9 desaturase pathway. Considering CLA isomers, they are also bioconverted by desaturases and the elongation pathway, but the significance of this conversion is not fully understood. 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subjects | Biochemistry Biochemistry, Molecular Biology conjugated linoleic acids Life Sciences metabolism Trans fatty acids |
title | Metabolism of trans and conjugated fatty acids |
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