Metabolism of trans and conjugated fatty acids

Trans fatty acids (FA) enter all the metabolic pathways of bioconversion, oxidation and lipid storage and are incorporated into all tissues. They also interfere with the polyunsaturated FA metabolic pathways. Among trans FA, major attention is paid to elaidic and vaccenic acids. The latter is biocon...

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Veröffentlicht in:European journal of lipid science and technology 2007-09, Vol.109 (9), p.930-934
Hauptverfasser: Chardigny, Jean-Michel, Clouet, Pierre, Combe, Nicole, Quignard-Boulangé, Annie, Schmitt, Bernard, Lagarde, Michel, Léger, Claude-Louis
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container_end_page 934
container_issue 9
container_start_page 930
container_title European journal of lipid science and technology
container_volume 109
creator Chardigny, Jean-Michel
Clouet, Pierre
Combe, Nicole
Quignard-Boulangé, Annie
Schmitt, Bernard
Lagarde, Michel
Léger, Claude-Louis
description Trans fatty acids (FA) enter all the metabolic pathways of bioconversion, oxidation and lipid storage and are incorporated into all tissues. They also interfere with the polyunsaturated FA metabolic pathways. Among trans FA, major attention is paid to elaidic and vaccenic acids. The latter is bioconverted into rumenic acid, a conjugated linoleic acid (CLA) isomer, through the Δ9 desaturase pathway. Considering CLA isomers, they are also bioconverted by desaturases and the elongation pathway, but the significance of this conversion is not fully understood. This review considers these different aspects, with particular attention to human data.
doi_str_mv 10.1002/ejlt.200600279
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subjects Biochemistry
Biochemistry, Molecular Biology
conjugated linoleic acids
Life Sciences
metabolism
Trans fatty acids
title Metabolism of trans and conjugated fatty acids
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