Age-impaired fluid homeostasis depends on the balance of IL-6/IGF-I in the rat supraoptic nuclei

Abstract Adaptive metabolic changes associated with bacterial infections are likely to cause dehydration. Activation of hypothalamic neurons in the supraoptic nucleus that release anti-diuretic arginine-vasopressin in plasma provides water retention. Aging is characterized by arginine-vasopressin ne...

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Veröffentlicht in:	Neurobiology of aging 2009-10, Vol.30 (10), p.1677-1692
Hauptverfasser:	Palin, K, Moreau, M.L, Orcel, H, Duvoid-Guillou, A, Rabié, A, Kelley, K.W, Moos, F
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Animals Arginine Vasopressin - blood Arginine Vasopressin - metabolism Astrocytes - physiology Autoantibodies - metabolism Biological and medical sciences Brain - physiopathology Cytokine Development. Senescence. Regeneration. Transplantation Diuresis - physiology Fundamental and applied biological sciences. Psychology Growth factor Homeostasis - physiology Hormone Insulin-Like Growth Factor I - metabolism Interleukin-6 - immunology Interleukin-6 - metabolism Internal Medicine Life Sciences Lipopolysaccharide Lipopolysaccharides - metabolism Male Neurohypophyseal system Neurology Neurons - physiology Proto-Oncogene Proteins c-fos - metabolism Rats Rats, Wistar Recombinant Proteins - metabolism RNA, Messenger - metabolism Supraoptic Nucleus - physiopathology Vasopressin Vertebrates: nervous system and sense organs Water balance Water-Electrolyte Imbalance - physiopathology
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