Effects of lifelong intervention with an oligofructose-enriched inulin in rats on general health and lifespan
Ageing is associated with changes in physiology and morphology; nutritional strategies to decrease morbidity and to prolong life are of high interest. The aim of the study was to investigate the effects of lifelong supplementation with an oligofructose-enriched inulin on morphological and biological...
Gespeichert in:
| Veröffentlicht in: | British journal of nutrition 2008-12, Vol.100 (6), p.1192-1199 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1199 |
|---|---|
| container_issue | 6 |
| container_start_page | 1192 |
| container_title | British journal of nutrition |
| container_volume | 100 |
| creator | Rozan, Pascale Nejdi, Amine Hidalgo, Sophie Bisson, Jean-François Desor, Didier Messaoudi, Michaël |
| description | Ageing is associated with changes in physiology and morphology; nutritional strategies to decrease morbidity and to prolong life are of high interest. The aim of the study was to investigate the effects of lifelong supplementation with an oligofructose-enriched inulin on morphological and biological markers and lifespan in male and female rats. Male and female rats, age 3 months, were randomised into two groups to receive either a diet with 10 % of an oligofructose-enriched inulin (Synergy1) or a standard diet (control) for 27 months. The rats were weighed every 2 weeks and their food intake was evaluated on four successive days every 4–6 weeks. Samples were taken at 12, 18 and 24 months of age. During the whole intervention period, male rats receiving Synergy1 (SYN1-M) displayed lower body weight, cholesterol and plasma triacylglycerolaemia compared with the controls (Cont-M). The survival rate at 24 months of age of SYN1-M rats was 35·3 % greater than that of Cont-M rats. In female rats, the Synergy1 supplementation (SYN1-F) group also reduced body weight, cholesterol and triacylglycerolaemia levels, but results were less consistent over the experiment. The survival rate at 24 months of age in SYN1-F rats was 33·3 % greater compared with that of the control (Cont-F) group. To conclude, lifelong intervention with Synergy1 improved biological markers during ageing and survival rate (lifespan) of rats. |
| doi_str_mv | 10.1017/S0007114508975607 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_hal_p</sourceid><recordid>TN_cdi_hal_primary_oai_HAL_hal_02658869v1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><cupid>10_1017_S0007114508975607</cupid><sourcerecordid>69804949</sourcerecordid><originalsourceid>FETCH-LOGICAL-c539t-4beeb52e325a713baf0ab168f404028772e55dee77528d1b967973aae1625f3e3</originalsourceid><addsrcrecordid>eNp1kV1rFDEUhgdR7Fr9Ad7oIFjwYjQfk4-5rKW2woKWtVB6EzIzJ7up2WSbzFT99810ly0oXh2S9znvyZtTFK8x-ogRFp8WCCGBcc2QbATjSDwpZrgWrCKck6fFbJKrST8oXqR0k48So-Z5cYBljViNyKxYnxoD3ZDKYEpnDbjgl6X1A8Q78IMNvvxlh1WpfRmcXQYTx24ICSrw0XYr6DM7OutzKaOebHy5BA9Ru3IF2j209g_OaaP9y-KZ0S7Bq109LC6_nP44Oa_m386-nhzPq47RZqjqFqBlBChhWmDaaoN0i7k0NcqPlkIQYKwHEIIR2eO24aIRVGvAnDBDgR4WH7a-K-3UJtq1jn9U0FadH8_VdIcIZ1Ly5g5n9mjLbmK4HSENam1TB85pD2FMijcS1U3dZPDdX-BNGKPPORTBVFLEKMkQ3kJdDClFMPvxGKlpaeqfpeWeNzvjsV1D_9ix21IG3u8AnTrtTNS-s2nPkcmJ1DJz1ZazaYDfe13Hn4oLKpjiZxfq4vv11dXnBVPXmX-75Y0OSi9j9rxcEIQpwkxSzqfPobs4et1G2y_hMfT_A90DJvTFqA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>213830532</pqid></control><display><type>article</type><title>Effects of lifelong intervention with an oligofructose-enriched inulin in rats on general health and lifespan</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Free Full-Text Journals in Chemistry</source><source>Cambridge University Press Journals Complete</source><creator>Rozan, Pascale ; Nejdi, Amine ; Hidalgo, Sophie ; Bisson, Jean-François ; Desor, Didier ; Messaoudi, Michaël</creator><creatorcontrib>Rozan, Pascale ; Nejdi, Amine ; Hidalgo, Sophie ; Bisson, Jean-François ; Desor, Didier ; Messaoudi, Michaël</creatorcontrib><description>Ageing is associated with changes in physiology and morphology; nutritional strategies to decrease morbidity and to prolong life are of high interest. The aim of the study was to investigate the effects of lifelong supplementation with an oligofructose-enriched inulin on morphological and biological markers and lifespan in male and female rats. Male and female rats, age 3 months, were randomised into two groups to receive either a diet with 10 % of an oligofructose-enriched inulin (Synergy1) or a standard diet (control) for 27 months. The rats were weighed every 2 weeks and their food intake was evaluated on four successive days every 4–6 weeks. Samples were taken at 12, 18 and 24 months of age. During the whole intervention period, male rats receiving Synergy1 (SYN1-M) displayed lower body weight, cholesterol and plasma triacylglycerolaemia compared with the controls (Cont-M). The survival rate at 24 months of age of SYN1-M rats was 35·3 % greater than that of Cont-M rats. In female rats, the Synergy1 supplementation (SYN1-F) group also reduced body weight, cholesterol and triacylglycerolaemia levels, but results were less consistent over the experiment. The survival rate at 24 months of age in SYN1-F rats was 33·3 % greater compared with that of the control (Cont-F) group. To conclude, lifelong intervention with Synergy1 improved biological markers during ageing and survival rate (lifespan) of rats.</description><identifier>ISSN: 0007-1145</identifier><identifier>EISSN: 1475-2662</identifier><identifier>DOI: 10.1017/S0007114508975607</identifier><identifier>PMID: 18405402</identifier><identifier>CODEN: BJNUAV</identifier><language>eng</language><publisher>Cambridge, UK: Cambridge University Press</publisher><subject>Ageing ; Aging - drug effects ; animal models ; Animals ; Biological and medical sciences ; Biological markers ; Biomarkers - blood ; Blood Glucose - metabolism ; Body Composition - drug effects ; Body weight ; Cholesterol ; Cholesterol - blood ; Diet ; Drug Evaluation, Preclinical ; Eating - drug effects ; elderly ; elderly nutrition ; experimental diets ; Feeding. Feeding behavior ; Female ; Females ; Food and Nutrition ; Fundamental and applied biological sciences. Psychology ; gender differences ; Glucose ; health status ; Human subjects ; inulin ; Inulin - pharmacology ; Laboratory animals ; Life Sciences ; Life span ; Lipid Metabolism ; Longevity - drug effects ; Male ; Nutrition research ; nutritional intervention ; oligofructose ; Oligofructose-enriched inulin ; Oligosaccharides - pharmacology ; Rats ; Rats, Sprague-Dawley ; Rodents ; senescence ; Survival ; Synergy1 ; Triglycerides - blood ; Vertebrates: anatomy and physiology, studies on body, several organs or systems ; Weight Gain - drug effects</subject><ispartof>British journal of nutrition, 2008-12, Vol.100 (6), p.1192-1199</ispartof><rights>Copyright © The Authors 2008</rights><rights>2009 INIST-CNRS</rights><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c539t-4beeb52e325a713baf0ab168f404028772e55dee77528d1b967973aae1625f3e3</citedby><cites>FETCH-LOGICAL-c539t-4beeb52e325a713baf0ab168f404028772e55dee77528d1b967973aae1625f3e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.cambridge.org/core/product/identifier/S0007114508975607/type/journal_article$$EHTML$$P50$$Gcambridge$$H</linktohtml><link.rule.ids>164,230,314,776,780,881,27903,27904,55606</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=20897248$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18405402$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://hal.inrae.fr/hal-02658869$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Rozan, Pascale</creatorcontrib><creatorcontrib>Nejdi, Amine</creatorcontrib><creatorcontrib>Hidalgo, Sophie</creatorcontrib><creatorcontrib>Bisson, Jean-François</creatorcontrib><creatorcontrib>Desor, Didier</creatorcontrib><creatorcontrib>Messaoudi, Michaël</creatorcontrib><title>Effects of lifelong intervention with an oligofructose-enriched inulin in rats on general health and lifespan</title><title>British journal of nutrition</title><addtitle>Br J Nutr</addtitle><description>Ageing is associated with changes in physiology and morphology; nutritional strategies to decrease morbidity and to prolong life are of high interest. The aim of the study was to investigate the effects of lifelong supplementation with an oligofructose-enriched inulin on morphological and biological markers and lifespan in male and female rats. Male and female rats, age 3 months, were randomised into two groups to receive either a diet with 10 % of an oligofructose-enriched inulin (Synergy1) or a standard diet (control) for 27 months. The rats were weighed every 2 weeks and their food intake was evaluated on four successive days every 4–6 weeks. Samples were taken at 12, 18 and 24 months of age. During the whole intervention period, male rats receiving Synergy1 (SYN1-M) displayed lower body weight, cholesterol and plasma triacylglycerolaemia compared with the controls (Cont-M). The survival rate at 24 months of age of SYN1-M rats was 35·3 % greater than that of Cont-M rats. In female rats, the Synergy1 supplementation (SYN1-F) group also reduced body weight, cholesterol and triacylglycerolaemia levels, but results were less consistent over the experiment. The survival rate at 24 months of age in SYN1-F rats was 33·3 % greater compared with that of the control (Cont-F) group. To conclude, lifelong intervention with Synergy1 improved biological markers during ageing and survival rate (lifespan) of rats.</description><subject>Ageing</subject><subject>Aging - drug effects</subject><subject>animal models</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Biological markers</subject><subject>Biomarkers - blood</subject><subject>Blood Glucose - metabolism</subject><subject>Body Composition - drug effects</subject><subject>Body weight</subject><subject>Cholesterol</subject><subject>Cholesterol - blood</subject><subject>Diet</subject><subject>Drug Evaluation, Preclinical</subject><subject>Eating - drug effects</subject><subject>elderly</subject><subject>elderly nutrition</subject><subject>experimental diets</subject><subject>Feeding. Feeding behavior</subject><subject>Female</subject><subject>Females</subject><subject>Food and Nutrition</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>gender differences</subject><subject>Glucose</subject><subject>health status</subject><subject>Human subjects</subject><subject>inulin</subject><subject>Inulin - pharmacology</subject><subject>Laboratory animals</subject><subject>Life Sciences</subject><subject>Life span</subject><subject>Lipid Metabolism</subject><subject>Longevity - drug effects</subject><subject>Male</subject><subject>Nutrition research</subject><subject>nutritional intervention</subject><subject>oligofructose</subject><subject>Oligofructose-enriched inulin</subject><subject>Oligosaccharides - pharmacology</subject><subject>Rats</subject><subject>Rats, Sprague-Dawley</subject><subject>Rodents</subject><subject>senescence</subject><subject>Survival</subject><subject>Synergy1</subject><subject>Triglycerides - blood</subject><subject>Vertebrates: anatomy and physiology, studies on body, several organs or systems</subject><subject>Weight Gain - drug effects</subject><issn>0007-1145</issn><issn>1475-2662</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp1kV1rFDEUhgdR7Fr9Ad7oIFjwYjQfk4-5rKW2woKWtVB6EzIzJ7up2WSbzFT99810ly0oXh2S9znvyZtTFK8x-ogRFp8WCCGBcc2QbATjSDwpZrgWrCKck6fFbJKrST8oXqR0k48So-Z5cYBljViNyKxYnxoD3ZDKYEpnDbjgl6X1A8Q78IMNvvxlh1WpfRmcXQYTx24ICSrw0XYr6DM7OutzKaOebHy5BA9Ru3IF2j209g_OaaP9y-KZ0S7Bq109LC6_nP44Oa_m386-nhzPq47RZqjqFqBlBChhWmDaaoN0i7k0NcqPlkIQYKwHEIIR2eO24aIRVGvAnDBDgR4WH7a-K-3UJtq1jn9U0FadH8_VdIcIZ1Ly5g5n9mjLbmK4HSENam1TB85pD2FMijcS1U3dZPDdX-BNGKPPORTBVFLEKMkQ3kJdDClFMPvxGKlpaeqfpeWeNzvjsV1D_9ix21IG3u8AnTrtTNS-s2nPkcmJ1DJz1ZazaYDfe13Hn4oLKpjiZxfq4vv11dXnBVPXmX-75Y0OSi9j9rxcEIQpwkxSzqfPobs4et1G2y_hMfT_A90DJvTFqA</recordid><startdate>20081201</startdate><enddate>20081201</enddate><creator>Rozan, Pascale</creator><creator>Nejdi, Amine</creator><creator>Hidalgo, Sophie</creator><creator>Bisson, Jean-François</creator><creator>Desor, Didier</creator><creator>Messaoudi, Michaël</creator><general>Cambridge University Press</general><general>Cambridge University Press (CUP)</general><scope>FBQ</scope><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7RV</scope><scope>7T5</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AN0</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><scope>1XC</scope></search><sort><creationdate>20081201</creationdate><title>Effects of lifelong intervention with an oligofructose-enriched inulin in rats on general health and lifespan</title><author>Rozan, Pascale ; Nejdi, Amine ; Hidalgo, Sophie ; Bisson, Jean-François ; Desor, Didier ; Messaoudi, Michaël</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c539t-4beeb52e325a713baf0ab168f404028772e55dee77528d1b967973aae1625f3e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Ageing</topic><topic>Aging - drug effects</topic><topic>animal models</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Biological markers</topic><topic>Biomarkers - blood</topic><topic>Blood Glucose - metabolism</topic><topic>Body Composition - drug effects</topic><topic>Body weight</topic><topic>Cholesterol</topic><topic>Cholesterol - blood</topic><topic>Diet</topic><topic>Drug Evaluation, Preclinical</topic><topic>Eating - drug effects</topic><topic>elderly</topic><topic>elderly nutrition</topic><topic>experimental diets</topic><topic>Feeding. Feeding behavior</topic><topic>Female</topic><topic>Females</topic><topic>Food and Nutrition</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>gender differences</topic><topic>Glucose</topic><topic>health status</topic><topic>Human subjects</topic><topic>inulin</topic><topic>Inulin - pharmacology</topic><topic>Laboratory animals</topic><topic>Life Sciences</topic><topic>Life span</topic><topic>Lipid Metabolism</topic><topic>Longevity - drug effects</topic><topic>Male</topic><topic>Nutrition research</topic><topic>nutritional intervention</topic><topic>oligofructose</topic><topic>Oligofructose-enriched inulin</topic><topic>Oligosaccharides - pharmacology</topic><topic>Rats</topic><topic>Rats, Sprague-Dawley</topic><topic>Rodents</topic><topic>senescence</topic><topic>Survival</topic><topic>Synergy1</topic><topic>Triglycerides - blood</topic><topic>Vertebrates: anatomy and physiology, studies on body, several organs or systems</topic><topic>Weight Gain - drug effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rozan, Pascale</creatorcontrib><creatorcontrib>Nejdi, Amine</creatorcontrib><creatorcontrib>Hidalgo, Sophie</creatorcontrib><creatorcontrib>Bisson, Jean-François</creatorcontrib><creatorcontrib>Desor, Didier</creatorcontrib><creatorcontrib>Messaoudi, Michaël</creatorcontrib><collection>AGRIS</collection><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Immunology Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>Hyper Article en Ligne (HAL)</collection><jtitle>British journal of nutrition</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rozan, Pascale</au><au>Nejdi, Amine</au><au>Hidalgo, Sophie</au><au>Bisson, Jean-François</au><au>Desor, Didier</au><au>Messaoudi, Michaël</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of lifelong intervention with an oligofructose-enriched inulin in rats on general health and lifespan</atitle><jtitle>British journal of nutrition</jtitle><addtitle>Br J Nutr</addtitle><date>2008-12-01</date><risdate>2008</risdate><volume>100</volume><issue>6</issue><spage>1192</spage><epage>1199</epage><pages>1192-1199</pages><issn>0007-1145</issn><eissn>1475-2662</eissn><coden>BJNUAV</coden><abstract>Ageing is associated with changes in physiology and morphology; nutritional strategies to decrease morbidity and to prolong life are of high interest. The aim of the study was to investigate the effects of lifelong supplementation with an oligofructose-enriched inulin on morphological and biological markers and lifespan in male and female rats. Male and female rats, age 3 months, were randomised into two groups to receive either a diet with 10 % of an oligofructose-enriched inulin (Synergy1) or a standard diet (control) for 27 months. The rats were weighed every 2 weeks and their food intake was evaluated on four successive days every 4–6 weeks. Samples were taken at 12, 18 and 24 months of age. During the whole intervention period, male rats receiving Synergy1 (SYN1-M) displayed lower body weight, cholesterol and plasma triacylglycerolaemia compared with the controls (Cont-M). The survival rate at 24 months of age of SYN1-M rats was 35·3 % greater than that of Cont-M rats. In female rats, the Synergy1 supplementation (SYN1-F) group also reduced body weight, cholesterol and triacylglycerolaemia levels, but results were less consistent over the experiment. The survival rate at 24 months of age in SYN1-F rats was 33·3 % greater compared with that of the control (Cont-F) group. To conclude, lifelong intervention with Synergy1 improved biological markers during ageing and survival rate (lifespan) of rats.</abstract><cop>Cambridge, UK</cop><pub>Cambridge University Press</pub><pmid>18405402</pmid><doi>10.1017/S0007114508975607</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0007-1145 |
| ispartof | British journal of nutrition, 2008-12, Vol.100 (6), p.1192-1199 |
| issn | 0007-1145 1475-2662 |
| language | eng |
| recordid | cdi_hal_primary_oai_HAL_hal_02658869v1 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Free Full-Text Journals in Chemistry; Cambridge University Press Journals Complete |
| subjects | Ageing Aging - drug effects animal models Animals Biological and medical sciences Biological markers Biomarkers - blood Blood Glucose - metabolism Body Composition - drug effects Body weight Cholesterol Cholesterol - blood Diet Drug Evaluation, Preclinical Eating - drug effects elderly elderly nutrition experimental diets Feeding. Feeding behavior Female Females Food and Nutrition Fundamental and applied biological sciences. Psychology gender differences Glucose health status Human subjects inulin Inulin - pharmacology Laboratory animals Life Sciences Life span Lipid Metabolism Longevity - drug effects Male Nutrition research nutritional intervention oligofructose Oligofructose-enriched inulin Oligosaccharides - pharmacology Rats Rats, Sprague-Dawley Rodents senescence Survival Synergy1 Triglycerides - blood Vertebrates: anatomy and physiology, studies on body, several organs or systems Weight Gain - drug effects |
| title | Effects of lifelong intervention with an oligofructose-enriched inulin in rats on general health and lifespan |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-27T18%3A08%3A02IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_hal_p&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effects%20of%20lifelong%20intervention%20with%20an%20oligofructose-enriched%20inulin%20in%20rats%20on%20general%20health%20and%20lifespan&rft.jtitle=British%20journal%20of%20nutrition&rft.au=Rozan,%20Pascale&rft.date=2008-12-01&rft.volume=100&rft.issue=6&rft.spage=1192&rft.epage=1199&rft.pages=1192-1199&rft.issn=0007-1145&rft.eissn=1475-2662&rft.coden=BJNUAV&rft_id=info:doi/10.1017/S0007114508975607&rft_dat=%3Cproquest_hal_p%3E69804949%3C/proquest_hal_p%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=213830532&rft_id=info:pmid/18405402&rft_cupid=10_1017_S0007114508975607&rfr_iscdi=true |